European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009–2014

Daan Dittmar; Wolfgang Uter; Andrea Bauer; Ana B. Fortina; Andreas J. Bircher; Magdalena Czarnecka-Operacz; Aleksandra Dugonik; Peter Elsner; Rosella Gallo; Sharizan A. Ghaffar; Anna Giménez-Arnau; Graham A. Johnston; Beata Kręcisz; Francesca L. Filon; Thomas Rustemeyer; Anna Sadowska-Przytocka; Javier Sánchez-Pérez; Axel Schnuch; Dagmar Simon; Radoslaw Spiewak; Philipp Spring; Maria T. Corradin; Skaidra Valiukevičienė; Marko Vok; Elke Weisshaar; Mark Wilkinson; Marie L. Schuttelaar; Werner Aberer; Barbara Ballmer-Weber; Jürgen Grabbe; Ulrike Beiteke; Jochen Brasch; Thomas Fuchs; Swen Malte John; Vera Mahler; Maria Pesonen; Riitta Jolanki; Tapio Rantanen; José Carlos Armario-Hita; Virginia Fernández-Redondo; Juan García-Gavín; Pedro Mercader; Inmaculada Ruiz; Juan Fco Silvestre; Anna Balato; Fabio Ayala; Andrea Peserico; Gondinga Sliuziaviciene; Marta Kieć-Świerczyńska; Tanja Kmecl; Maja Kalac Pandurovic; Nada Kecelj; Tomaž Lunder; Mojca Simončič Godnič; Mahbub M.U. Chowdhury; Susan M. Cooper; John S.C. English; Philippa Cousen; Helen L. Horne; David J. Gawkrodger; Catherine Holden; Ruth Sabroe; Cathy M. Green; Codagh M. King; Anthony D. Ormerod; Jane E. Samson; Barry Statham; Natalie Stone; Ian White

doi:10.1111/cod.12966

European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009–2014

Daan Dittmar, Wolfgang Uter, Andrea Bauer, Ana B. Fortina, Andreas J. Bircher, Magdalena Czarnecka-Operacz, Aleksandra Dugonik, Peter Elsner, Rosella Gallo, Sharizan A. Ghaffar, Anna Giménez-Arnau, Graham A. Johnston, Beata Kręcisz, Francesca L. Filon, Thomas Rustemeyer, Anna Sadowska-Przytocka, Javier Sánchez-Pérez, Axel Schnuch, Dagmar Simon, Radoslaw SpiewakPhilipp Spring, Maria T. Corradin, Skaidra Valiukevičienė, Marko Vok, Elke Weisshaar, Mark Wilkinson, Marie L. Schuttelaar, Werner Aberer, Barbara Ballmer-Weber, Jürgen Grabbe, Ulrike Beiteke, Jochen Brasch, Thomas Fuchs, Swen Malte John, Vera Mahler, Maria Pesonen, Riitta Jolanki, Tapio Rantanen, José Carlos Armario-Hita, Virginia Fernández-Redondo, Juan García-Gavín, Pedro Mercader, Inmaculada Ruiz, Juan Fco Silvestre, Anna Balato, Fabio Ayala, Andrea Peserico, Gondinga Sliuziaviciene, Marta Kieć-Świerczyńska, Tanja Kmecl, Maja Kalac Pandurovic, Nada Kecelj, Tomaž Lunder, Mojca Simončič Godnič, Mahbub M.U. Chowdhury, Susan M. Cooper, John S.C. English, Philippa Cousen, Helen L. Horne, David J. Gawkrodger, Catherine Holden, Ruth Sabroe, Cathy M. Green, Codagh M. King, Anthony D. Ormerod, Jane E. Samson, Barry Statham, Natalie Stone, Ian White

Department of Medicine

Research output: Contribution to journal › Article › Research › peer-review

14 Citations (Scopus)

Abstract

© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Background: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life. Objectives: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization. Methods: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed. Results: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization. Conclusions: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.

Original language	English
Pages (from-to)	373-385
Journal	Contact Dermatitis
Volume	78
Issue number	6
DOIs	https://doi.org/10.1111/cod.12966
Publication status	Published - 1 Jun 2018

Keywords

clinical epidemiology
contact allergy
patch test
polysensitization

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10.1111/cod.12966

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Dittmar, D., Uter, W., Bauer, A., Fortina, A. B., Bircher, A. J., Czarnecka-Operacz, M., Dugonik, A., Elsner, P., Gallo, R., Ghaffar, S. A., Giménez-Arnau, A., Johnston, G. A., Kręcisz, B., Filon, F. L., Rustemeyer, T., Sadowska-Przytocka, A., Sánchez-Pérez, J., Schnuch, A., Simon, D., ... White, I. (2018). European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009–2014. Contact Dermatitis, 78(6), 373-385. https://doi.org/10.1111/cod.12966

@article{4a8b525b87734c309841fec622fcc4f6,

title = "European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009–2014",

abstract = "{\textcopyright} 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Background: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life. Objectives: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization. Methods: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed. Results: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization. Conclusions: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.",

keywords = "clinical epidemiology, contact allergy, patch test, polysensitization",

author = "Daan Dittmar and Wolfgang Uter and Andrea Bauer and Fortina, {Ana B.} and Bircher, {Andreas J.} and Magdalena Czarnecka-Operacz and Aleksandra Dugonik and Peter Elsner and Rosella Gallo and Ghaffar, {Sharizan A.} and Anna Gim{\'e}nez-Arnau and Johnston, {Graham A.} and Beata Kr{\c e}cisz and Filon, {Francesca L.} and Thomas Rustemeyer and Anna Sadowska-Przytocka and Javier S{\'a}nchez-P{\'e}rez and Axel Schnuch and Dagmar Simon and Radoslaw Spiewak and Philipp Spring and Corradin, {Maria T.} and Skaidra Valiukevi{\v c}ienė and Marko Vok and Elke Weisshaar and Mark Wilkinson and Schuttelaar, {Marie L.} and Werner Aberer and Barbara Ballmer-Weber and J{\"u}rgen Grabbe and Ulrike Beiteke and Jochen Brasch and Thomas Fuchs and John, {Swen Malte} and Vera Mahler and Maria Pesonen and Riitta Jolanki and Tapio Rantanen and Armario-Hita, {Jos{\'e} Carlos} and Virginia Fern{\'a}ndez-Redondo and Juan Garc{\'i}a-Gav{\'i}n and Pedro Mercader and Inmaculada Ruiz and Silvestre, {Juan Fco} and Anna Balato and Fabio Ayala and Andrea Peserico and Gondinga Sliuziaviciene and Marta Kie{\'c}-{\'S}wierczy{\'n}ska and Tanja Kmecl and Pandurovic, {Maja Kalac} and Nada Kecelj and Toma{\v z} Lunder and {Simon{\v c}i{\v c} Godni{\v c}}, Mojca and Chowdhury, {Mahbub M.U.} and Cooper, {Susan M.} and English, {John S.C.} and Philippa Cousen and Horne, {Helen L.} and Gawkrodger, {David J.} and Catherine Holden and Ruth Sabroe and Green, {Cathy M.} and King, {Codagh M.} and Ormerod, {Anthony D.} and Samson, {Jane E.} and Barry Statham and Natalie Stone and Ian White",

year = "2018",

month = jun,

day = "1",

doi = "10.1111/cod.12966",

language = "English",

volume = "78",

pages = "373--385",

journal = "Contact Dermatitis",

issn = "0105-1873",

number = "6",

}

Dittmar, D, Uter, W, Bauer, A, Fortina, AB, Bircher, AJ, Czarnecka-Operacz, M, Dugonik, A, Elsner, P, Gallo, R, Ghaffar, SA, Giménez-Arnau, A, Johnston, GA, Kręcisz, B, Filon, FL, Rustemeyer, T, Sadowska-Przytocka, A, Sánchez-Pérez, J, Schnuch, A, Simon, D, Spiewak, R, Spring, P, Corradin, MT, Valiukevičienė, S, Vok, M, Weisshaar, E, Wilkinson, M, Schuttelaar, ML, Aberer, W, Ballmer-Weber, B, Grabbe, J, Beiteke, U, Brasch, J, Fuchs, T, John, SM, Mahler, V, Pesonen, M, Jolanki, R, Rantanen, T, Armario-Hita, JC, Fernández-Redondo, V, García-Gavín, J, Mercader, P, Ruiz, I, Silvestre, JF, Balato, A, Ayala, F, Peserico, A, Sliuziaviciene, G, Kieć-Świerczyńska, M, Kmecl, T, Pandurovic, MK, Kecelj, N, Lunder, T, Simončič Godnič, M, Chowdhury, MMU, Cooper, SM, English, JSC, Cousen, P, Horne, HL, Gawkrodger, DJ, Holden, C, Sabroe, R, Green, CM, King, CM, Ormerod, AD, Samson, JE, Statham, B, Stone, N & White, I 2018, 'European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009–2014', Contact Dermatitis, vol. 78, no. 6, pp. 373-385. https://doi.org/10.1111/cod.12966

TY - JOUR

T1 - European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009–2014

AU - Dittmar, Daan

AU - Uter, Wolfgang

AU - Bauer, Andrea

AU - Fortina, Ana B.

AU - Bircher, Andreas J.

AU - Czarnecka-Operacz, Magdalena

AU - Dugonik, Aleksandra

AU - Elsner, Peter

AU - Gallo, Rosella

AU - Ghaffar, Sharizan A.

AU - Giménez-Arnau, Anna

AU - Johnston, Graham A.

AU - Kręcisz, Beata

AU - Filon, Francesca L.

AU - Rustemeyer, Thomas

AU - Sadowska-Przytocka, Anna

AU - Sánchez-Pérez, Javier

AU - Schnuch, Axel

AU - Simon, Dagmar

AU - Spiewak, Radoslaw

AU - Spring, Philipp

AU - Corradin, Maria T.

AU - Valiukevičienė, Skaidra

AU - Vok, Marko

AU - Weisshaar, Elke

AU - Wilkinson, Mark

AU - Schuttelaar, Marie L.

AU - Aberer, Werner

AU - Ballmer-Weber, Barbara

AU - Grabbe, Jürgen

AU - Beiteke, Ulrike

AU - Brasch, Jochen

AU - Fuchs, Thomas

AU - John, Swen Malte

AU - Mahler, Vera

AU - Pesonen, Maria

AU - Jolanki, Riitta

AU - Rantanen, Tapio

AU - Armario-Hita, José Carlos

AU - Fernández-Redondo, Virginia

AU - García-Gavín, Juan

AU - Mercader, Pedro

AU - Ruiz, Inmaculada

AU - Silvestre, Juan Fco

AU - Balato, Anna

AU - Ayala, Fabio

AU - Peserico, Andrea

AU - Sliuziaviciene, Gondinga

AU - Kieć-Świerczyńska, Marta

AU - Kmecl, Tanja

AU - Pandurovic, Maja Kalac

AU - Kecelj, Nada

AU - Lunder, Tomaž

AU - Simončič Godnič, Mojca

AU - Chowdhury, Mahbub M.U.

AU - Cooper, Susan M.

AU - English, John S.C.

AU - Cousen, Philippa

AU - Horne, Helen L.

AU - Gawkrodger, David J.

AU - Holden, Catherine

AU - Sabroe, Ruth

AU - Green, Cathy M.

AU - King, Codagh M.

AU - Ormerod, Anthony D.

AU - Samson, Jane E.

AU - Statham, Barry

AU - Stone, Natalie

AU - White, Ian

PY - 2018/6/1

Y1 - 2018/6/1

N2 - © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Background: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life. Objectives: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization. Methods: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed. Results: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization. Conclusions: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.

AB - © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Background: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life. Objectives: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization. Methods: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed. Results: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization. Conclusions: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.

KW - clinical epidemiology

KW - contact allergy

KW - patch test

KW - polysensitization

U2 - 10.1111/cod.12966

DO - 10.1111/cod.12966

M3 - Article

SN - 0105-1873

VL - 78

SP - 373

EP - 385

JO - Contact Dermatitis

JF - Contact Dermatitis

IS - 6

ER -

European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009–2014

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