TY - JOUR
T1 - Ethyl N-(diphenylmethylene)glycinate as anionic glycine equivalent. Monoalkylation, dialkylation and michael additions under solid-liquid phase-transfer catalysis
AU - López, Anna
AU - Moreno-Mañas, Marcial
AU - Pleixats, Roser
AU - Roglans, Anna
AU - Ezquerra, Jesús
AU - Pedregal, Concepción
PY - 1996/6/10
Y1 - 1996/6/10
N2 - Ethyl N-(diphenylmethylene)glycinate, 1, undergoes monoalkylations, dialkylations and Michael additions to ethylenic and acetylenic acceptors under appropriate solid-liquid phase transfer catalysis conditions. Further transformations of the α-disubstituted ketimines lead to α-alkylated aspartic and glutamic acid derivatives 10, 15, 19 and 26, to bicyclic amino acids or derivatives featuring pyrazolone and isoxazolone moieties 30 and 33, and to α-substituted (E)-3,4-dehydroglutamic acids. Copyright © 1996 Elsevier Science Ltd.
AB - Ethyl N-(diphenylmethylene)glycinate, 1, undergoes monoalkylations, dialkylations and Michael additions to ethylenic and acetylenic acceptors under appropriate solid-liquid phase transfer catalysis conditions. Further transformations of the α-disubstituted ketimines lead to α-alkylated aspartic and glutamic acid derivatives 10, 15, 19 and 26, to bicyclic amino acids or derivatives featuring pyrazolone and isoxazolone moieties 30 and 33, and to α-substituted (E)-3,4-dehydroglutamic acids. Copyright © 1996 Elsevier Science Ltd.
UR - https://www.scopus.com/pages/publications/0030013951
U2 - 10.1016/0040-4020(96)00395-X
DO - 10.1016/0040-4020(96)00395-X
M3 - Article
SN - 0040-4020
VL - 52
SP - 8365
EP - 8386
JO - Tetrahedron
JF - Tetrahedron
IS - 24
ER -