Essential mixed cryoglobulinaemia and hepatitis-B virus

F. Garcia-Bragado, M. Vilardell, V. Fonollosa

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11 Citations (Scopus)


Essential mixed cryoglobulinaemia is a nosological entity described by Meltzer and Franklin in 1966 and characterized by asthenia, arthralgias, purpura, glomerulonephritis and mixed IgM-IgG cryoglobulinaemia. Hepatitis-B virus (HBV) markers were studied in the sera and cryoprecipitates of 6 patients with the syndrome. Five (83.3%) had at least one HBV marker and three (50%) had HBsAg either in the serum or in the cryoprecipitate. HBV therefore seems to be involved in the pathogenesis of essential mixed cryoglobulinaemia in a large number of cases.
Original languageEnglish
Pages (from-to)2955-2957
JournalNouvelle Presse Medicale
Issue number36
Publication statusPublished - 1 Jan 1981


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