Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: Comparative genomic hybridization analyses in metaphase II oocytes and their first polar body

Albert Obradors, Mariona Rius, Juliana Cuzzi, Gemma Daina, Cristina Gutiérrez-Mateo, Aïda Pujol, Fernando Marina, Carmen Márquez, Jordi Benet, Joaquima Navarro

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Abstract

The aim of this work is to analyze, using the comparative genomic hybridization technique, the frequencies and the mechanisms involved in the production of aneuploidy events in donor oocytes. The results showed that 32.1% of them were aneuploid, with 51.7% of those originating from first meiotic division errors and 48.3% from the presence of aneuploid oogonium. © 2010 American Society for Reproductive Medicine.
Original languageEnglish
Pages (from-to)675-679
JournalFertility and Sterility
Volume93
Issue number2
DOIs
Publication statusPublished - 15 Jan 2010

Keywords

  • aneuploid oogonie
  • CGH
  • IVF donor
  • Oocyte aneuploidy

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