Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: Comparative genomic hybridization analyses in metaphase II oocytes and their first polar body

Albert Obradors; Mariona Rius; Juliana Cuzzi; Gemma Daina; Cristina Gutiérrez-Mateo; Aïda Pujol; Fernando Marina; Carmen Márquez; Jordi Benet; Joaquima Navarro

doi:10.1016/j.fertnstert.2009.08.050

Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: Comparative genomic hybridization analyses in metaphase II oocytes and their first polar body

Albert Obradors, Mariona Rius, Juliana Cuzzi, Gemma Daina, Cristina Gutiérrez-Mateo, Aïda Pujol, Fernando Marina, Carmen Márquez, Jordi Benet, Joaquima Navarro

Research output: Contribution to journal › Article › Research › peer-review

23 Citations (Scopus)

Abstract

The aim of this work is to analyze, using the comparative genomic hybridization technique, the frequencies and the mechanisms involved in the production of aneuploidy events in donor oocytes. The results showed that 32.1% of them were aneuploid, with 51.7% of those originating from first meiotic division errors and 48.3% from the presence of aneuploid oogonium. © 2010 American Society for Reproductive Medicine.

Original language	English
Pages (from-to)	675-679
Journal	Fertility and Sterility
Volume	93
Issue number	2
DOIs	https://doi.org/10.1016/j.fertnstert.2009.08.050
Publication status	Published - 15 Jan 2010

Keywords

aneuploid oogonie
CGH
IVF donor
Oocyte aneuploidy

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10.1016/j.fertnstert.2009.08.050

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Obradors, A., Rius, M., Cuzzi, J., Daina, G., Gutiérrez-Mateo, C., Pujol, A., Marina, F., Márquez, C., Benet, J., & Navarro, J. (2010). Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: Comparative genomic hybridization analyses in metaphase II oocytes and their first polar body. Fertility and Sterility, 93(2), 675-679. https://doi.org/10.1016/j.fertnstert.2009.08.050

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abstract = "The aim of this work is to analyze, using the comparative genomic hybridization technique, the frequencies and the mechanisms involved in the production of aneuploidy events in donor oocytes. The results showed that 32.1% of them were aneuploid, with 51.7% of those originating from first meiotic division errors and 48.3% from the presence of aneuploid oogonium. {\textcopyright} 2010 American Society for Reproductive Medicine.",

keywords = "aneuploid oogonie, CGH, IVF donor, Oocyte aneuploidy",

author = "Albert Obradors and Mariona Rius and Juliana Cuzzi and Gemma Daina and Cristina Guti{\'e}rrez-Mateo and A{\"i}da Pujol and Fernando Marina and Carmen M{\'a}rquez and Jordi Benet and Joaquima Navarro",

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doi = "10.1016/j.fertnstert.2009.08.050",

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Obradors, A, Rius, M, Cuzzi, J, Daina, G, Gutiérrez-Mateo, C, Pujol, A, Marina, F, Márquez, C, Benet, J & Navarro, J 2010, 'Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: Comparative genomic hybridization analyses in metaphase II oocytes and their first polar body', Fertility and Sterility, vol. 93, no. 2, pp. 675-679. https://doi.org/10.1016/j.fertnstert.2009.08.050

Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: Comparative genomic hybridization analyses in metaphase II oocytes and their first polar body. / Obradors, Albert; Rius, Mariona; Cuzzi, Juliana et al.

In: Fertility and Sterility, Vol. 93, No. 2, 15.01.2010, p. 675-679.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: Comparative genomic hybridization analyses in metaphase II oocytes and their first polar body

AU - Obradors, Albert

AU - Rius, Mariona

AU - Cuzzi, Juliana

AU - Daina, Gemma

AU - Gutiérrez-Mateo, Cristina

AU - Pujol, Aïda

AU - Marina, Fernando

AU - Márquez, Carmen

AU - Benet, Jordi

AU - Navarro, Joaquima

PY - 2010/1/15

Y1 - 2010/1/15

N2 - The aim of this work is to analyze, using the comparative genomic hybridization technique, the frequencies and the mechanisms involved in the production of aneuploidy events in donor oocytes. The results showed that 32.1% of them were aneuploid, with 51.7% of those originating from first meiotic division errors and 48.3% from the presence of aneuploid oogonium. © 2010 American Society for Reproductive Medicine.

AB - The aim of this work is to analyze, using the comparative genomic hybridization technique, the frequencies and the mechanisms involved in the production of aneuploidy events in donor oocytes. The results showed that 32.1% of them were aneuploid, with 51.7% of those originating from first meiotic division errors and 48.3% from the presence of aneuploid oogonium. © 2010 American Society for Reproductive Medicine.

KW - aneuploid oogonie

KW - CGH

KW - IVF donor

KW - Oocyte aneuploidy

U2 - 10.1016/j.fertnstert.2009.08.050

DO - 10.1016/j.fertnstert.2009.08.050

M3 - Article

SN - 0015-0282

VL - 93

SP - 675

EP - 679

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 2

ER -

Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: Comparative genomic hybridization analyses in metaphase II oocytes and their first polar body

Abstract

Keywords

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