Enhancing the electrochemical response of myoglobin with carbon nanotube electrodes

M. J. Esplandiu, M. Pacios, L. Cyganek, J. Bartroli, M. Del Valle

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Abstract

In this paper, the electrochemical behavior of different myoglobin-modified carbon electrodes is evaluated. In particular, the performance of voltammetric biosensors made of forest-like carbon nanotubes, carbon nanotube composites and graphite composites is compared by monitoring mainly the electrocatalytic reduction of H 2 O 2 by myoglobin and their corresponding electroanalytical characteristics. Graphite composites showed the worst electroanalytical performance, exhibiting a small linear range, a limit of detection (LOD) of 9 × 10 -5 M and low sensitivity. However, it was found that the electrochemical response was enhanced with the use of carbon nanotube-based electrodes with LOD up to 5 × 10 -8 M, higher sensitivities and wider linear range response. On the one hand, in the case of the CNT epoxy composite, the improvement in the response can be mainly attributed to its more porous surface which allows the immobilization of higher amounts of the electroactive protein. On the other hand, in the case of the forest-like CNT electrodes, the enhancement is due to an increase in the electron transfer kinetics. These findings encourage the use of myoglobin-modified carbon nanotube electrodes as potential (bio)sensors of H 2 O 2 or O 2 in biology, microbiology and environmental fields. © 2009 IOP Publishing Ltd.
Original languageEnglish
Article number355502
JournalNanotechnology
Volume20
Issue number35
DOIs
Publication statusPublished - 2 Sep 2009

Fingerprint Dive into the research topics of 'Enhancing the electrochemical response of myoglobin with carbon nanotube electrodes'. Together they form a unique fingerprint.

Cite this