Enhanced terahertz sensitivity for glucose detection with a hydrogel platform embedded with Au nanoparticles

Jingjing Zhao, Shaohua Lu, Julio Bastos-Arrieta, Cristina Palet, Yiling Sun, Renheng Wang, Zhengfang Qian, Shuting Fan*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

Abstract

We presented a strategy for enhancing the sensitivity of terahertz glucose sensing with a hydrogel platform pre-embedded with Au nanoparticles. Physiological-level glucose solutions ranging from 0 to 0.8 mg/mL were measured and the extracted absorption coefficients can be clearly distinguished compared to traditional terahertz time domain spectroscopy performed directly on aqueous solutions. Further, Isotherm models were applied to successfully describe the relationship between the absorption coefficient and the glucose concentration (R2 = 0.9977). Finally, the origin of the sensitivity enhancement was investigated and verified to be the pH change induced by the catalysis of Au nanoparticles to glucose oxidation.

Original languageEnglish
Pages (from-to)4021-4031
Number of pages11
JournalBiomedical Optics Express
Volume13
Issue number7
DOIs
Publication statusPublished - 1 Jul 2022

Fingerprint

Dive into the research topics of 'Enhanced terahertz sensitivity for glucose detection with a hydrogel platform embedded with Au nanoparticles'. Together they form a unique fingerprint.

Cite this