Gamma interferon responses of spleen cells in mice were examined during postchemotherapy relapse of intraperitoneally induced latent tuberculous infection. The mycobacterial extract RUTI, which prevented the relapse, significantly enhanced the immune responses to secreted and structural recombinant mycobacterial antigens, suggesting that RUTI-mediated protection was mediated by activated T cells. Copyright © 2008, American Society for Microbiology. All Rights Reserved.
|Journal||Clinical and Vaccine Immunology|
|Publication status||Published - 1 Nov 2008|