Endoscopic surgery in the skull base unit: Experience in the first 72 cases

Juan R. Gras-Cabrerizo, Fernando Muñoz-Hernández, Joan R. Montserrat-Gili, Pere Tresserras-Ribo, Manuel de Juan-Delago, Susan M. Webb, Anna Aulinas-Masó, Beatriz Martín-Huerta, Joan Molet-Teixidó, Miquel Quer-Agustí, Humbert Massegur-Solench

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6 Citations (Scopus)


Introduction: A multidisciplinary team is essential to develop and expand the indications in endonasal endoscopic skull base surgery.The aim of this study was to present our experience in a group of patients with skull base lesions treated using endonasal endoscopic approach. Methods: From January 2008 to January 2012, 72 patients with skull base involvement were diagnosed and treated in our centre. Results: The mean patient age was 53 years. The different pathologies included 36 pituitary adenomas, 10 cerebrospinal fluid leaks and 5 inverted papillomas as the most frequent pathologies. We performed a transsphenoidal transellar approach in 45 cases, a transmaxillary transpterygoid approach in 4 cases and a transnasal expanded approach in 6 cases. We performed an ethmoidal/sphenoidal approach in 12 patients and a Draf IIb/III procedure in four cases. Total resection was achieved in 61% of patients with pituitary adenomas, subtotal in 22% and partial in 17%. Successful repair was achieved in 86% of CSF leaks. No recurrences were observed in patients with inverted papilloma. Complications were observed in 21 patients (29%), 6 being major complications. Conclusions: Our centre stresses the importance of multidisciplinary collaboration in endoscopic endonasal skull base surgery. © 2012 Elsevier España, S.L.
Original languageEnglish
Pages (from-to)169-175
JournalActa Otorrinolaringologica Espanola
Issue number3
Publication statusPublished - 1 May 2013


  • Cerebrospinal fluid leak
  • Endoscopic surgery
  • Multidisciplinary team
  • Pituitary adenoma
  • Skull base


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