Enantioselective synthesis of hydroxy α-amino acids. (-)-erythro- and (-) -threo-γ-hydroxynorvalines

Jesus Ariza, Josep Font, Rosa M. Ortuño

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)


The amino acids (-)-erythro- and (-)-threo-γ-hydroxynorvaline have been synthesized from D-ribonolactone, 6, as single chiral precursor. Moreover, β-hydrox-αazido- γ-valerolactones 12a and 12b have been also prepared from 6 in two different alternative ways. These compounds afford β,γ-dihydroxy-α -amino acids 18a and 18b with Darabino and D-ribo configuration, respectively. © 1990.
Original languageEnglish
Pages (from-to)1931-1942
Issue number6
Publication statusPublished - 1 Jan 1990


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