© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim A general protocol for the enantioselective synthesis of 3-heterosubstituted-2-amino-1-ols was developed based on metal- free intramolecular regio- and stereoselective diene aziridination and regioselective opening. Kinetic resolution of the resulting (1′-NR1R2 and 1′-SR)-4-oxazolidinones was performed using ABCs organocatalysts, expanding the application of this methodology.
|Journal||Chemistry - A European Journal|
|Publication status||Published - 25 Sep 2019|
- ABC catalysts
- carbamates kinetic resolution
- metal-free aziridination
- sphingosine analogues
- vinylaziridines synthesis