Electrocatalyzed O 2 response of myoglobin immobilized on multi-walled carbon nanotube forest electrodes

M. Pacios, M. Del Valle, J. Bartroli, M. J. Esplandiu

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Direct electrochemistry and activity of myoglobin (Mb) immobilized on carbon nanotube (CNT) forest electrodes were investigated by probing mainly its electrocatalytical response towards oxygen. The protein was anchored on the CNT electrodes through carbodiimide coupling, which was shown to provide long term stability. The electrochemical response was monitored as a function of oxygen concentration and pH. Conformational changes together with the consequent loss of oxygen affinity were recorded at low pH, which delimits the operative range of the Mb/CNT electrodes for sensing purposes. In general, it can be concluded that CNT forests constitute suitable platforms for Mb attachment without compromising the protein bioactivity and by keeping at the same time the direct electron exchange with the heme core. All these characteristics confer to the protein modified CNT system promising properties for the implementation of (bio)sensor devices with impact in the clinical and environmental field.

Original languageEnglish
Pages (from-to)6132-6138
Number of pages7
JournalJournal of Nanoscience and Nanotechnology
Volume9
Issue number10
DOIs
Publication statusPublished - Oct 2009

Keywords

  • Amperometric sensor
  • Carbon nanotube
  • Direct electrochemistry
  • Electrocatalysis
  • Myoglobin

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