Electrical stimulation of cells through photovoltaic microcell arrays

Carolina Vargas-Estevez; Andreu Blanquer; Gonzalo Murillo; Marcos Duque; Leonardo Barrios; Carme Nogués; Elena Ibañez; Jaume Esteve

doi:10.1016/j.nanoen.2018.07.012

Electrical stimulation of cells through photovoltaic microcell arrays

Carolina Vargas-Estevez^*, Andreu Blanquer, Gonzalo Murillo, Marcos Duque, Leonardo Barrios, Carme Nogués, Elena Ibañez^*, Jaume Esteve

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)

Abstract

© 2018 Elsevier Ltd Electrical stimulation may influence cell behavior associated with proliferation, differentiation, and migration, among others. The need for electrical tools to interact with living cells has pushed the technology to progressively develop less invasive devices. Technologies like energy harvesting have enabled wireless biological applications. Here we report the use of a photovoltaic microcell array (PVMA) based on silicon, as a wire-free interface to stimulate single cells with high spatial resolution. We demonstrate the effectivity of this microtool on osteoblast cells. The electrical stimulation triggered intracellular calcium transients as a response in 46% of the cells. The reduced dimension of the PVMA and its capacity to work in visible light show its potential for the wireless life science explorations.

Original language	English
Pages (from-to)	571-578
Journal	Nano Energy
Volume	51
DOIs	https://doi.org/10.1016/j.nanoen.2018.07.012
Publication status	Published - 1 Sept 2018

Keywords

Electrical cell stimulation
Photovoltaic array
Silicon solar microcell

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.nanoen.2018.07.012

Cite this

@article{f3c064de7b494e96b9ad212cc0f50ea2,

title = "Electrical stimulation of cells through photovoltaic microcell arrays",

abstract = "{\textcopyright} 2018 Elsevier Ltd Electrical stimulation may influence cell behavior associated with proliferation, differentiation, and migration, among others. The need for electrical tools to interact with living cells has pushed the technology to progressively develop less invasive devices. Technologies like energy harvesting have enabled wireless biological applications. Here we report the use of a photovoltaic microcell array (PVMA) based on silicon, as a wire-free interface to stimulate single cells with high spatial resolution. We demonstrate the effectivity of this microtool on osteoblast cells. The electrical stimulation triggered intracellular calcium transients as a response in 46% of the cells. The reduced dimension of the PVMA and its capacity to work in visible light show its potential for the wireless life science explorations.",

keywords = "Electrical cell stimulation, Photovoltaic array, Silicon solar microcell",

author = "Carolina Vargas-Estevez and Andreu Blanquer and Gonzalo Murillo and Marcos Duque and Leonardo Barrios and Carme Nogu{\'e}s and Elena Iba{\~n}ez and Jaume Esteve",

year = "2018",

month = sep,

day = "1",

doi = "10.1016/j.nanoen.2018.07.012",

language = "English",

volume = "51",

pages = "571--578",

journal = "Nano Energy",

issn = "2211-2855",

publisher = "Elsevier BV",

}

TY - JOUR

T1 - Electrical stimulation of cells through photovoltaic microcell arrays

AU - Vargas-Estevez, Carolina

AU - Blanquer, Andreu

AU - Murillo, Gonzalo

AU - Duque, Marcos

AU - Barrios, Leonardo

AU - Nogués, Carme

AU - Ibañez, Elena

AU - Esteve, Jaume

PY - 2018/9/1

Y1 - 2018/9/1

N2 - © 2018 Elsevier Ltd Electrical stimulation may influence cell behavior associated with proliferation, differentiation, and migration, among others. The need for electrical tools to interact with living cells has pushed the technology to progressively develop less invasive devices. Technologies like energy harvesting have enabled wireless biological applications. Here we report the use of a photovoltaic microcell array (PVMA) based on silicon, as a wire-free interface to stimulate single cells with high spatial resolution. We demonstrate the effectivity of this microtool on osteoblast cells. The electrical stimulation triggered intracellular calcium transients as a response in 46% of the cells. The reduced dimension of the PVMA and its capacity to work in visible light show its potential for the wireless life science explorations.

AB - © 2018 Elsevier Ltd Electrical stimulation may influence cell behavior associated with proliferation, differentiation, and migration, among others. The need for electrical tools to interact with living cells has pushed the technology to progressively develop less invasive devices. Technologies like energy harvesting have enabled wireless biological applications. Here we report the use of a photovoltaic microcell array (PVMA) based on silicon, as a wire-free interface to stimulate single cells with high spatial resolution. We demonstrate the effectivity of this microtool on osteoblast cells. The electrical stimulation triggered intracellular calcium transients as a response in 46% of the cells. The reduced dimension of the PVMA and its capacity to work in visible light show its potential for the wireless life science explorations.

KW - Electrical cell stimulation

KW - Photovoltaic array

KW - Silicon solar microcell

U2 - 10.1016/j.nanoen.2018.07.012

DO - 10.1016/j.nanoen.2018.07.012

M3 - Article

SN - 2211-2855

VL - 51

SP - 571

EP - 578

JO - Nano Energy

JF - Nano Energy

ER -

Electrical stimulation of cells through photovoltaic microcell arrays

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this