Efficient synthesis of α,β-unsaturated γ-lactones linked to sugars

Amélia P. Rauter, José Figueiredo, Maria Ismael, Tana Canda, Josep Font, Marta Figueredo

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)


A series of structurally diverse unsaturated sugar-derived lactones has been prepared. α,β-Butenolides were introduced to the sugar moiety starting from epoxides, while α-methylene-γ-lactones were constructed from a carbonyl precursor, either an aldehyde, a ketone or a lactone. In the last case, an unprecedented Reformatsky-type reaction has been developed. © 2001 Published by Elsevier Science Ltd.
Original languageEnglish
Pages (from-to)1131-1146
JournalTetrahedron Asymmetry
Issue number8
Publication statusPublished - 21 May 2001


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