Effects of preoperative administration of meloxicam on whole blood platelet aggregation, buccal mucosal bleeding time, and haematological indices in dogs undergoing elective ovariohysterectomy

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Abstract

The purpose of the study was to evaluate the effect of preoperative administration of meloxicam, a non-steroidal anti-inflammatory drug used for pain control, on primary haemostasis in dogs. Twenty healthy female dogs undergoing elective ovariohysterectomy were enrolled in the study. Sixty minutes before pre-anaesthesia, a single dose of meloxicam (0.2 mg/kg) was randomly administered intravenously (IV) to 10 dogs (treatment group) while control dogs received an equivalent volume of saline solution IV. Platelet aggregation, buccal mucosa bleeding time, platelet count and haematological indices were measured at 0, 1, 6 and 24 h after administration of meloxicam. Since significant differences between groups were not observed for any of the measured parameters, preoperative administration of meloxicam may be used for pain control before elective ovariohysterectomy in healthy dogs, without compromising primary haemostasis. © 2004 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)138-140
JournalVeterinary Journal
Volume170
Issue number1
DOIs
Publication statusPublished - 1 Jul 2005

Keywords

  • Cyclooxygenase-2
  • Nonsteroidal anti-inflammatory drug
  • Pain
  • Primary haemostasis
  • Surgery

Fingerprint Dive into the research topics of 'Effects of preoperative administration of meloxicam on whole blood platelet aggregation, buccal mucosal bleeding time, and haematological indices in dogs undergoing elective ovariohysterectomy'. Together they form a unique fingerprint.

Cite this