Effects of aging on the zona pellucida surface of mouse oocytes

Jose Egozcue Cuixart, Maria Del Carme Nogues Sanmiquel, Montserrat Ponsa Fontanals, Francesca Vidal Dominguez

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)


In a scanning microscopy study of mouse oocytes from immature, young, and aged females and of oocytes aged in vivo or in vitro, we have observed four types of zona pellucida, which we classify as types A, B, C, and D. Oocyte aging gives rise to a significant increase in predegenerative (type C) oocytes; this type of zona pellucida surface could result from a zona hardening effect and decrease the rate of fertilization of the oocytes affected. © 1988 Plenum Publishing Corporation.
Original languageEnglish
Pages (from-to)225-229
JournalJournal of in Vitro Fertilization and Embryo Transfer
Issue number4
Publication statusPublished - 1 Aug 1988


  • mouse oocytes
  • oocyte aging
  • scanning electron microscopy
  • zona pellucida


Dive into the research topics of 'Effects of aging on the zona pellucida surface of mouse oocytes'. Together they form a unique fingerprint.

Cite this