In a scanning microscopy study of mouse oocytes from immature, young, and aged females and of oocytes aged in vivo or in vitro, we have observed four types of zona pellucida, which we classify as types A, B, C, and D. Oocyte aging gives rise to a significant increase in predegenerative (type C) oocytes; this type of zona pellucida surface could result from a zona hardening effect and decrease the rate of fertilization of the oocytes affected. © 1988 Plenum Publishing Corporation.
|Journal||Journal of in Vitro Fertilization and Embryo Transfer|
|Publication status||Published - 1 Aug 1988|
- mouse oocytes
- oocyte aging
- scanning electron microscopy
- zona pellucida