Effectiveness of rituximab in severe Wegener's granulomatosis: Report of two cases and review of the literature

Joaquim Oristrell; Guillermina Bejarano; Rosa Jordana; Manuel Monteagudo; Begoña Marí; Arnau Casanovas; Carles Tolosa

doi:https://doi.org/10.2174/1874306400903010094

Effectiveness of rituximab in severe Wegener's granulomatosis: Report of two cases and review of the literature

Joaquim Oristrell, Guillermina Bejarano, Rosa Jordana, Manuel Monteagudo, Begoña Marí, Arnau Casanovas, Carles Tolosa

Research output: Contribution to journal › Review article › Research › peer-review

14 Citations (Scopus)

Abstract

We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener's granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous experience with the use of rituximab in the treatment of WG is presented. © Oristrell et al.; Licensee Bentham Open.

Original language	English
Pages (from-to)	94-99
Journal	Open Respiratory Medicine Journal
Volume	3
DOIs	https://doi.org/10.2174/1874306400903010094
Publication status	Published - 1 Dec 2009

Keywords

Rescue treatment
Rituximab
Wegener's granulomatosis

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title = "Effectiveness of rituximab in severe Wegener's granulomatosis: Report of two cases and review of the literature",

abstract = "We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener's granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous experience with the use of rituximab in the treatment of WG is presented. {\textcopyright} Oristrell et al.; Licensee Bentham Open.",

keywords = "Rescue treatment, Rituximab, Wegener's granulomatosis",

author = "Joaquim Oristrell and Guillermina Bejarano and Rosa Jordana and Manuel Monteagudo and Bego{\~n}a Mar{\'i} and Arnau Casanovas and Carles Tolosa",

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T1 - Effectiveness of rituximab in severe Wegener's granulomatosis: Report of two cases and review of the literature

AU - Oristrell, Joaquim

AU - Bejarano, Guillermina

AU - Jordana, Rosa

AU - Monteagudo, Manuel

AU - Marí, Begoña

AU - Casanovas, Arnau

AU - Tolosa, Carles

PY - 2009/12/1

Y1 - 2009/12/1

N2 - We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener's granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous experience with the use of rituximab in the treatment of WG is presented. © Oristrell et al.; Licensee Bentham Open.

AB - We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener's granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous experience with the use of rituximab in the treatment of WG is presented. © Oristrell et al.; Licensee Bentham Open.

KW - Rescue treatment

KW - Rituximab

KW - Wegener's granulomatosis

U2 - https://doi.org/10.2174/1874306400903010094

DO - https://doi.org/10.2174/1874306400903010094

M3 - Review article

SN - 1874-3064

VL - 3

SP - 94

EP - 99

JO - Open Respiratory Medicine Journal

JF - Open Respiratory Medicine Journal

ER -

Effectiveness of rituximab in severe Wegener's granulomatosis: Report of two cases and review of the literature

Abstract

Keywords

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