Effectiveness of rituximab in severe Wegener's granulomatosis: Report of two cases and review of the literature

Joaquim Oristrell, Guillermina Bejarano, Rosa Jordana, Manuel Monteagudo, Begoña Marí, Arnau Casanovas, Carles Tolosa

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    11 Citations (Scopus)

    Abstract

    We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener's granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous experience with the use of rituximab in the treatment of WG is presented. © Oristrell et al.; Licensee Bentham Open.
    Original languageEnglish
    Pages (from-to)94-99
    JournalOpen Respiratory Medicine Journal
    Volume3
    DOIs
    Publication statusPublished - 1 Dec 2009

    Keywords

    • Rescue treatment
    • Rituximab
    • Wegener's granulomatosis

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