An interesting and simple approach to effective multiple-solvent suppression is proposed using the basic principles of the excitation sculpting methodology. Flat baseline and ultra-clean NMR spectra are usually obtained under standard conditions using a modified double pulsed field gradient echo scheme in samples containing mixtures of non-deuterated solvents. The simple performance of such an approach, the high tolerance to experimental mis-settings, the impressive level of solvent suppression and the easy incorporation of the proposed scheme in multi-dimensional NMR experiments make this method suitable for possible applications in liquid chromatography NMR. © 1998 John Wiley & Sons, Ltd.
|Journal||Magnetic Resonance in Chemistry|
|Publication status||Published - 1 Apr 1998|
- Excitation sculpting
- Liquid chromatography
- Multiple solvent suppression
- Pulsed field gradient