Effect of X-rays on germ cells in female fetuses of Rattus norvegicus irradiated at three different times of gestation

R. Pujol; L. Cusidó; A. Rubio; J. Egozcue; M. Garcia

doi:https://doi.org/10.1016/0027-5107(96)00067-X

Effect of X-rays on germ cells in female fetuses of Rattus norvegicus irradiated at three different times of gestation

R. Pujol, L. Cusidó, A. Rubio, J. Egozcue, M. Garcia

Research output: Contribution to journal › Article › Research › peer-review

8 Citations (Scopus)

Abstract

We analyzed the effect of X-rays on the number of recoverable germ cells in female rat fetuses irradiated at three different times of gestation: 14 days (oogonia), 16 days (leptotene) and 18 days (zygotene). Our results show that irradiation significantly decreases the number of germ cells, and increases the incidence of synaptonemal complex fragmentation. The different sensitivity of the germ cells to irradiation could depend on the meiotic stage at the time of irradiation.

Original language	English
Pages (from-to)	247-253
Journal	Mutation Research
Volume	356
DOIs	https://doi.org/10.1016/0027-5107(96)00067-X
Publication status	Published - 23 Sept 1996

Keywords

Female germ cell
Genotoxicity
Meiosis
Synaptonemal complex

Access to Document

https://doi.org/10.1016/0027-5107(96)00067-X

Cite this

@article{2c618c4a2dce4702bb5a29516ca31c44,

title = "Effect of X-rays on germ cells in female fetuses of Rattus norvegicus irradiated at three different times of gestation",

abstract = "We analyzed the effect of X-rays on the number of recoverable germ cells in female rat fetuses irradiated at three different times of gestation: 14 days (oogonia), 16 days (leptotene) and 18 days (zygotene). Our results show that irradiation significantly decreases the number of germ cells, and increases the incidence of synaptonemal complex fragmentation. The different sensitivity of the germ cells to irradiation could depend on the meiotic stage at the time of irradiation.",

keywords = "Female germ cell, Genotoxicity, Meiosis, Synaptonemal complex",

author = "R. Pujol and L. Cusid{\'o} and A. Rubio and J. Egozcue and M. Garcia",

year = "1996",

month = sep,

day = "23",

doi = "https://doi.org/10.1016/0027-5107(96)00067-X",

language = "English",

volume = "356",

pages = "247--253",

}

TY - JOUR

T1 - Effect of X-rays on germ cells in female fetuses of Rattus norvegicus irradiated at three different times of gestation

AU - Pujol, R.

AU - Cusidó, L.

AU - Rubio, A.

AU - Egozcue, J.

AU - Garcia, M.

PY - 1996/9/23

Y1 - 1996/9/23

N2 - We analyzed the effect of X-rays on the number of recoverable germ cells in female rat fetuses irradiated at three different times of gestation: 14 days (oogonia), 16 days (leptotene) and 18 days (zygotene). Our results show that irradiation significantly decreases the number of germ cells, and increases the incidence of synaptonemal complex fragmentation. The different sensitivity of the germ cells to irradiation could depend on the meiotic stage at the time of irradiation.

AB - We analyzed the effect of X-rays on the number of recoverable germ cells in female rat fetuses irradiated at three different times of gestation: 14 days (oogonia), 16 days (leptotene) and 18 days (zygotene). Our results show that irradiation significantly decreases the number of germ cells, and increases the incidence of synaptonemal complex fragmentation. The different sensitivity of the germ cells to irradiation could depend on the meiotic stage at the time of irradiation.

KW - Female germ cell

KW - Genotoxicity

KW - Meiosis

KW - Synaptonemal complex

U2 - https://doi.org/10.1016/0027-5107(96)00067-X

DO - https://doi.org/10.1016/0027-5107(96)00067-X

M3 - Article

VL - 356

SP - 247

EP - 253

ER -

Effect of X-rays on germ cells in female fetuses of Rattus norvegicus irradiated at three different times of gestation

Abstract

Keywords

Access to Document

Fingerprint

Cite this