Effect of X-rays on germ cells in female fetuses of Rattus norvegicus irradiated at three different times of gestation

R. Pujol, L. Cusidó, A. Rubio, J. Egozcue, M. Garcia

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7 Citations (Scopus)

Abstract

We analyzed the effect of X-rays on the number of recoverable germ cells in female rat fetuses irradiated at three different times of gestation: 14 days (oogonia), 16 days (leptotene) and 18 days (zygotene). Our results show that irradiation significantly decreases the number of germ cells, and increases the incidence of synaptonemal complex fragmentation. The different sensitivity of the germ cells to irradiation could depend on the meiotic stage at the time of irradiation.
Original languageEnglish
Pages (from-to)247-253
JournalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume356
DOIs
Publication statusPublished - 23 Sep 1996

Keywords

  • Female germ cell
  • Genotoxicity
  • Meiosis
  • Synaptonemal complex

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