Effect of sucralfate on gastric: Intramucosal pH in critically ill patients

X. Calvet; F. Baigorri; M. Duarte; D. Joseph; P. Saura; A. Mas; C. Royo; A. Artigas

doi:10.1007/s001340050402

Effect of sucralfate on gastric: Intramucosal pH in critically ill patients

X. Calvet, F. Baigorri, M. Duarte, D. Joseph, P. Saura, A. Mas, C. Royo, A. Artigas

Research output: Contribution to journal › Article › Research › peer-review

14 Citations (Scopus)

Abstract

Objective: To determine whether sucralfate administration affects the tonometric measurement of gastric intramucosal pH (pHi). Design: Non-randomized observational study. Setting: General intensive care unit of a teaching hospital. Patients: Twenty critically ill, mechanically ventilated, consecutively admitted patients requiring an arterial catheter and nasogastric tube. Interventions: Tonometer placement and sucralfate administration. Measurements and main results: We simultaneously determined tonometer saline PCO2 (PCO2i), arterial blood gases, pH of gastric juice and pHi. These parameters were evaluated immediately before sucralfate administration, and 2 h and 4 h after. We did not detect any change in either PCO2i or pHi after sucralfate administration (PCO2i: basal 6.4 ± 1.7, 2 h 6.3 ± 1.7, 4 h 6.3 ± 1.7; pHi: basal 7.35 ± 0.13, 2 h 7.36 ± 0.12, 4 h 7.36 ± 0.12). Conclusions: Sucralfate does not affect the tonometric measurement of PCO2i and pHi.

Original language	English
Pages (from-to)	738-742
Journal	Intensive Care Medicine
Volume	23
Issue number	7
DOIs	https://doi.org/10.1007/s001340050402
Publication status	Published - 22 Sept 1997

Keywords

Critically ill patients
Gastric intramucosal pH
Sucralfate
Tonometry

Access to Document

10.1007/s001340050402

Cite this

@article{c1a1798edd0545e7bb953f6d999f939c,

title = "Effect of sucralfate on gastric: Intramucosal pH in critically ill patients",

abstract = "Objective: To determine whether sucralfate administration affects the tonometric measurement of gastric intramucosal pH (pHi). Design: Non-randomized observational study. Setting: General intensive care unit of a teaching hospital. Patients: Twenty critically ill, mechanically ventilated, consecutively admitted patients requiring an arterial catheter and nasogastric tube. Interventions: Tonometer placement and sucralfate administration. Measurements and main results: We simultaneously determined tonometer saline PCO2 (PCO2i), arterial blood gases, pH of gastric juice and pHi. These parameters were evaluated immediately before sucralfate administration, and 2 h and 4 h after. We did not detect any change in either PCO2i or pHi after sucralfate administration (PCO2i: basal 6.4 ± 1.7, 2 h 6.3 ± 1.7, 4 h 6.3 ± 1.7; pHi: basal 7.35 ± 0.13, 2 h 7.36 ± 0.12, 4 h 7.36 ± 0.12). Conclusions: Sucralfate does not affect the tonometric measurement of PCO2i and pHi.",

keywords = "Critically ill patients, Gastric intramucosal pH, Sucralfate, Tonometry",

author = "X. Calvet and F. Baigorri and M. Duarte and D. Joseph and P. Saura and A. Mas and C. Royo and A. Artigas",

year = "1997",

month = sep,

day = "22",

doi = "10.1007/s001340050402",

language = "English",

volume = "23",

pages = "738--742",

journal = "Intensive Care Medicine",

issn = "0342-4642",

number = "7",

}

TY - JOUR

T1 - Effect of sucralfate on gastric: Intramucosal pH in critically ill patients

AU - Calvet, X.

AU - Baigorri, F.

AU - Duarte, M.

AU - Joseph, D.

AU - Saura, P.

AU - Mas, A.

AU - Royo, C.

AU - Artigas, A.

PY - 1997/9/22

Y1 - 1997/9/22

N2 - Objective: To determine whether sucralfate administration affects the tonometric measurement of gastric intramucosal pH (pHi). Design: Non-randomized observational study. Setting: General intensive care unit of a teaching hospital. Patients: Twenty critically ill, mechanically ventilated, consecutively admitted patients requiring an arterial catheter and nasogastric tube. Interventions: Tonometer placement and sucralfate administration. Measurements and main results: We simultaneously determined tonometer saline PCO2 (PCO2i), arterial blood gases, pH of gastric juice and pHi. These parameters were evaluated immediately before sucralfate administration, and 2 h and 4 h after. We did not detect any change in either PCO2i or pHi after sucralfate administration (PCO2i: basal 6.4 ± 1.7, 2 h 6.3 ± 1.7, 4 h 6.3 ± 1.7; pHi: basal 7.35 ± 0.13, 2 h 7.36 ± 0.12, 4 h 7.36 ± 0.12). Conclusions: Sucralfate does not affect the tonometric measurement of PCO2i and pHi.

AB - Objective: To determine whether sucralfate administration affects the tonometric measurement of gastric intramucosal pH (pHi). Design: Non-randomized observational study. Setting: General intensive care unit of a teaching hospital. Patients: Twenty critically ill, mechanically ventilated, consecutively admitted patients requiring an arterial catheter and nasogastric tube. Interventions: Tonometer placement and sucralfate administration. Measurements and main results: We simultaneously determined tonometer saline PCO2 (PCO2i), arterial blood gases, pH of gastric juice and pHi. These parameters were evaluated immediately before sucralfate administration, and 2 h and 4 h after. We did not detect any change in either PCO2i or pHi after sucralfate administration (PCO2i: basal 6.4 ± 1.7, 2 h 6.3 ± 1.7, 4 h 6.3 ± 1.7; pHi: basal 7.35 ± 0.13, 2 h 7.36 ± 0.12, 4 h 7.36 ± 0.12). Conclusions: Sucralfate does not affect the tonometric measurement of PCO2i and pHi.

KW - Critically ill patients

KW - Gastric intramucosal pH

KW - Sucralfate

KW - Tonometry

U2 - 10.1007/s001340050402

DO - 10.1007/s001340050402

M3 - Article

SN - 0342-4642

VL - 23

SP - 738

EP - 742

JO - Intensive Care Medicine

JF - Intensive Care Medicine

IS - 7

ER -

Effect of sucralfate on gastric: Intramucosal pH in critically ill patients

Abstract

Keywords

Access to Document

Fingerprint

Cite this