TY - JOUR
T1 - Effect of statin and fibrate treatment on inflammation in type 2 diabetes. A randomized, cross-over study
AU - Wägner, Ana María
AU - Sánchez-Quesada, Jose Luis
AU - Benítez, Sonia
AU - Bancells, Cristina
AU - Ordóñez-Llanos, Jordi
AU - Pérez, Antonio
PY - 2011/7/1
Y1 - 2011/7/1
N2 - A randomized, crossover study compared the effects of atorvastatin, gemfibrozil and their combination on inflammatory markers in type 2 diabetes. C-reactive protein (CRP), lipoprotein-associated phospholipase A2 (Lp-PLA2), secretory phospholipase A2 (sPLA2), interleukin 8 (IL8), monocyte chemotactic protein 1 (MCP1) and tumor necrosis factor α (TNFα) were measured. Both lipid-lowering drugs had positive, complementary and additive effects on inflammatory markers, which were closely related to baseline inflammatory status. © 2011 Elsevier Ireland Ltd.
AB - A randomized, crossover study compared the effects of atorvastatin, gemfibrozil and their combination on inflammatory markers in type 2 diabetes. C-reactive protein (CRP), lipoprotein-associated phospholipase A2 (Lp-PLA2), secretory phospholipase A2 (sPLA2), interleukin 8 (IL8), monocyte chemotactic protein 1 (MCP1) and tumor necrosis factor α (TNFα) were measured. Both lipid-lowering drugs had positive, complementary and additive effects on inflammatory markers, which were closely related to baseline inflammatory status. © 2011 Elsevier Ireland Ltd.
KW - Atorvastatin
KW - C-reactive protein
KW - Gemfibrozil
KW - Inflammation markers
KW - Phospholipase A2
U2 - 10.1016/j.diabres.2011.03.009
DO - 10.1016/j.diabres.2011.03.009
M3 - Article
VL - 93
IS - 1
ER -
