Effect of porcine circovirus type 2 (PCV2) load in serum on average daily weight gain during the postweaning period

S. López-Soria, M. Sibila, M. Nofrarías, M. Calsamiglia, E. G. Manzanilla, H. Ramírez-Mendoza, A. Mínguez, J. M. Serrano, O. Marín, F. Joisel, C. Charreyre, J. Segalés

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8 Citations (Scopus)

Abstract

© 2014 Elsevier B.V. Porcine circovirus type 2 (PCV2) is a ubiquitous virus that mainly affects nursery and fattening pigs causing systemic disease (PCV2-SD) or subclinical infection. A characteristic sign in both presentations is reduction of average daily weight gain (ADWG). The present study aimed to assess the relationship between PCV2 load in serum and ADWG from 3 (weaning) to 21 weeks of age (slaughter) (ADWG 3-21). Thus, three different boar lines were used to inseminate sows from two PCV2-SD affected farms. One or two pigs per sow were selected (60, 61 and 51 piglets from Pietrain, Pietrain×Large White and Duroc×Large White boar lines, respectively). Pigs were bled at 3, 9, 15 and 21 weeks of age and weighted at 3 and 21 weeks. Area under the curve of the viral load at all sampling times (AUCqPCR 3-21) was calculated for each animal according to standard and real time quantitative PCR results; this variable was categorized as "negative or low" (<104.3 PCV2 genome copies/ml of serum), "medium" (≥104.3 to ≤105.3) and "high" (>105.3). Data regarding sex, PCV2 antibody titre at weaning and sow parity was also collected. A generalized linear model was performed, obtaining that paternal genetic line and AUCqPCR 3-21 were related to ADWG 3-21. ADWG 3-21 (mean±typical error) for "negative or low", "medium" and "high" AUCqPCR 3-21 was 672±9, 650±12 and 603±16g/day, respectively, showing significant differences among them. This study describes different ADWG performances in 3 pig populations that suffered from different degrees of PCV2 viraemia.
Original languageEnglish
Pages (from-to)296-301
JournalVeterinary Microbiology
Volume174
Issue number3-4
DOIs
Publication statusPublished - 1 Jan 2014

Keywords

  • Average daily weight gain
  • Genetics
  • PCV2-subclinical infection (PCV2-SI)
  • PCV2-systemic disease (PCV2-SD)
  • Porcine circovirus type 2 (PCV2)
  • Viral load

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