Abstract
In order to evaluate the effect of several intercalating compounds on crossing-over in Drosophila melanogaster females, acridine orange, acriflavine, chloroquine, ethidium bromide and quinacrine were fed separately to larvae of y ct f/+++ genotype. Our results show that acridine orange, acriflavine and ethidium bromide increase significantly the recombination frequency at the ct-f region and support the view that, for intercalating agents, there is a relationship between clastogenic activity and female recombination induction. © 1985 Birkhäuser Verlag.
| Original language | English |
|---|---|
| Pages (from-to) | 1078-1079 |
| Journal | Experientia |
| Volume | 41 |
| DOIs | |
| Publication status | Published - 1 Aug 1985 |
Keywords
- Drosophila melanogaster
- clastogenic activity
- crossing-over
- intercalating mutagens
- recombination induction