Effect of chronic clonidine treatment on urinary growth hormone excretion and linear growth in children with short stature

Anna Sanmarti, A. Lucas, M. L. Granada, I. Salinas, J. L. Reverter, J. M. Cuatrecasas, M. Foz, L. Audi

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Abstract

Eleven prepubertal children with short stature were treated with clonidine (0.15 mg/m2 daily) for a period of 1 year. The effect of this drug was evaluated on both clinical (growth velocity, height standard deviation scores for chronological age and bone age) and hormonal (urinary growth hormone excretion and insulin-like growth factor I) parameters. Our study shows that long-term clonidine administration in children with shon stature did not result in significant differences in growth velocity, height standard deviation scores for chronological age and bone age, insulin-like growth factor I or in urinary growth hormone excretion. © 1990 S. Karger AG, Basel.
Original languageEnglish
Pages (from-to)193-196
JournalHormone Research in Paediatrics
Volume34
Issue number5-6
DOIs
Publication statusPublished - 1 Jan 1990

Keywords

  • Clonidine
  • Short stature
  • Urinary growth hormone excretion

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    Sanmarti, A., Lucas, A., Granada, M. L., Salinas, I., Reverter, J. L., Cuatrecasas, J. M., Foz, M., & Audi, L. (1990). Effect of chronic clonidine treatment on urinary growth hormone excretion and linear growth in children with short stature. Hormone Research in Paediatrics, 34(5-6), 193-196. https://doi.org/10.1159/000181824