Effect of 6β-methylprednisolone on mouse pregnancy rate

Esther Velilla, Mark Grossmann, Josep Egozcue, Josep Santaló

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)


The aim of this study was to evaluate the effect of methylprednisolone on the pregnancy rate in mice. For this reason, zona pellucida-intact and zona pellucida-free embryos at the blastocyst stage were transferred to recipient mice at day 2.5 of pseudopregnancy. Embryo transfer was performed into non-immunodepressed and immunodepressed groups of recipient mice using 0.3 or 0.6 μg/g of 6β-methylprednisolone. A higher implantation and developmental rate of zona-free embryos transferred to the immunodepressed group of recipients was observed after using the higher dose of methylprednisolone.
Original languageEnglish
Pages (from-to)207-210
JournalHuman Reproduction
Issue number1
Publication statusPublished - 1 Jan 1999


  • Developmental rate
  • Embryo transfer
  • Immunodepression
  • Implantation rate
  • Methylprednisolone


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