Early amniocentesis with the filtration technique: Neonatal outcome in 123 singleton pregnancies

I. Farrán, M. A. Sánchez, C. Mediano, A. Plaja, A. Guzmán, A. M. De La Riva, L. Cabero

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5 Citations (Scopus)

Abstract

Objective: To evaluate results of a prospective study of pregnancies in which early amniocentesis with the filtration technique was performed at 10-13 weeks' gestation (mean 12.3 weeks' gestation). Methods: 123 singleton pregnancies in which early amniocentesis with the modified filtration technique was performed at 10-13 weeks' gestation (mean 12.3 weeks' gestation). The amniotic fluid was aspirated into the syringe and reinjected through the filter. Results: All the procedures were performed successfully by a single needle insertion. Neither dry taps nor filtration failures occurred. The mean time of amniocentesis was 4.02 min (95% confidence interval, 3 min and 36 s to 4 min and 18 s). The karyotyping success rate was 99.2%. Temporary amniotic fluid leakage occurred in three women (2.4%). There were 110 (89.4%) live births. Two cases of stillbirth occurred at week 38 and week 40. Two unintended losses occurred within three weeks after sampling (1.62%). Another additional unintended fetal death was notified at the 20-week screening ultrasonography. The total fetal-loss rate was 10.6%. In one case, talipes equinovarus was detected at the 20-week screening ultrasound study. Conclusions: Further studies are needed to determine the risk of amniotic leakage and its relation to duration of the procedure in patients undergoing early amnifiltration. Copyright © 2002 John Wiley & Sons, Ltd.
Original languageEnglish
Pages (from-to)859-863
JournalPrenatal Diagnosis
Volume22
DOIs
Publication statusPublished - 1 Oct 2002

Keywords

  • Congenital anomalies
  • Early amniocentesis
  • Filtration amniocentesis
  • Premature rupture of membranes
  • Risks

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