Dynamics, integrability and topology for some classes of Kolmogorov Hamiltonian systems in R<inf>+</inf>⁴

© 2016 Elsevier Inc. In this paper we first give the sufficient and necessary conditions in order that two classes of polynomial Kolmogorov systems in R+4 are Hamiltonian systems. Then we study the integrability of these Hamiltonian systems in the Liouville sense. Finally, we investigate the global dynamics of the completely integrable Lotka–Volterra Hamiltonian systems in R+4. As an application of the invariant subsets of these systems, we obtain topological classifications of the 3-submanifolds in R+4 defined by the hypersurfaces axy+bzw+cx2y+dxy2+ez2w+fzw2=h, where a,b,c,d,e,f,w and h are real constants.