Drosophila polymorphism database (DPDB) a portal for nucleotide polymorphism in Drosophila

Sònia Casillas, Raquel Egea, Natalia Petit, Casey M. Bergman, Antonio Barbadilla

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

As a growing number of haplotypic sequences from resequencing studies are now accumulating for Drosophila in the main primary sequence databases, collectively they can now be used to describe the general pattern of nucleotide variation across species and genes of this genus. The Drosophila Polymorphism Database (DPDB) is a secondary database that provides a collection of all well-annotated polymorphic sequences in Drosophila together with their associated diversity measures and options for reanalysis of the data that greatly facilitate both multi-locus and multi-species diversity studies in one of the most important groups of model organisms. Here we describe the state-of-the-art of the DPDB database and provide a step-by-step guide to all its searching and analytic capabilities. Finally, we illustrate its usefulness through selected examples. DPDB is freely available at http://dpdb.uab.cat. © 2007 Landes Bioscience.
Original languageEnglish
Pages (from-to)205-211
JournalFly
Volume1
Issue number4
DOIs
Publication statusPublished - 1 Jan 2007

Keywords

  • Bioinformatics of genetic diversity
  • Database
  • DNA polymorphism
  • Drosophila
  • Large scale analyses
  • Nucleotide variation
  • Population genetics

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