Abstract
A DOT-ELISA method for detection of 2,3-diacyl-trehalose (DAT, previously referred to as SL-IV antigen) and triglycosyl phenol phthiocerol di-mycocerosate (PGL-Tb 1) antigens from Mycobacterium tuberculosis is described. The method enabled the detection of both antigens in 14 clinical isolates of M. tuberculosis from different geographic origins; the presence of the glycolipids was confirmed by chemical analysis. It was therefore concluded that the synthesis of both of these compounds is characteristic of the species. © 1992.
Original language | English |
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Pages (from-to) | 327-331 |
Journal | Research in Microbiology |
Volume | 143 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Jan 1992 |
Keywords
- DAT
- Détection
- DOT-ELISA
- Glycolipid
- Mycobacterium tuberculosis
- PGL-Tb1