Does thrombolysis benefit patients with lacunar syndrome?

Dolores Cocho, Roberto Belvís, Joan Martí-Fàbregas, Yolanda Bravo, Aitziber Aleu, Javier Pagonabarraga, Laura Molina-Porcel, Jorge Díaz-Manera, Luis San Roman, María Martínez-Lage, Alejandro Martínez, Mireia Moreno, Josep Lluis Martí-Vilalta

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)


The efficacy of thrombolysis in clinical stroke subtypes is unclear. We compared the benefit of intravenous rt-PA in 11 patients with lacunar syndrome with that in 33 patients with a non-lacunar syndrome. Patients were matched by NIHSS score and time to treatment. Although no statistically significant differences were detected in outcome, the benefit was greater in the non-lacunar syndrome group. Copyright © 2006 S. Karger AG.
Original languageEnglish
Pages (from-to)70-73
JournalEuropean Neurology
Issue number2
Publication statusPublished - 1 May 2006


  • Lacunar syndrome
  • Stroke etiology
  • Thrombolysis


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