Distribution of intrachromosomal telomeric sequences (ITS) on Macaca fascicularis (Primates) chromosomes and their implication for chromosome evolution

A. Ruiz-Herrera, F. García, C. Azzalin, E. Giulotto, J. Egozcue, M. Ponsà, Montserrat Garcia

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

Abstract

The intrachromosomal location of the telomeric sequence in the crab-eating macaque, Macaca fascicularis (F. Cercopithecidae, Catarrhini) has been analysed by fluorescent in situ hybridisation with a long synthetic (TTAGGG)n probe. A total of 237 metaphases was analysed. As expected, all telomeres hybridised with the probe and 90 intrachromosomal loci with different hybridisation frequecies were also detected. The chromosomal location of interstitial telomeric sequences in M. fascicularis and in Homo sapiens was then compared, 37 sites (41.11%) being found to be conserved. Some of these sequences can be derived from rearrangements, such as inversions (MFA13q23) or fusions (MFA2p13 and MFA13p12), that have taken place during karyotype evolution. © Springer-Verlag 2002.
Original languageEnglish
Pages (from-to)578-586
JournalHuman Genetics
Volume110
Issue number6
DOIs
Publication statusPublished - 1 Jun 2002

Fingerprint Dive into the research topics of 'Distribution of intrachromosomal telomeric sequences (ITS) on Macaca fascicularis (Primates) chromosomes and their implication for chromosome evolution'. Together they form a unique fingerprint.

  • Cite this