Serum lipoprotein(a) (Lp(a) concentrations were measured in a Catalonian (Spain) population. We measured serum Lp(a) by a quantitative immunoturbidimetric method in 678 subjects, 359 males (mean age, 51 ± 14 years) and 319 females (mean age 50 ± 13 years) free of coronary heart disease and cerebrovascular disease and not on medications known to affect lipids and lipoproteins. The associations between serum Lp(a) levels and other cardiovascular risk factors were also examined. The Lp(a) frequency distribution was highly skewed to lower levels. Median (and reference intervals) were 0.20 g/L (<0.03 -1.49 g/L) in men and 0.18 g/L (<0.03 - 1.29 g/L) in women. Serum Lp(a) values did not differ significantly between sexes. Values of more than 0.89 g/L were above the 90th percentile and values of more than 0.47 g/L were above the 75th percentile in both men and women. Serum Lp(a) levels increased with the age of the population and with triglycerides in the women. The positive associations of serum Lp(a) levels with total cholesterol and low density lipoprotein (LDL) cholesterol were not significant after correction for the estimated contribution of Lp(a) cholesterol to total and LDL cholesterol.
|Publication status||Published - 1 Dec 1996|