Dissociation between corticosterone and growth hormone adaptation to chronic stress in the rat

A. Armario, J. M. Castellanos, J. Balasch

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Abstract

We have studied the effect of acute and chronic stress on corticosterone and growth hormone (GH) serum levels in male Wistar rats. Both acute noise-light stress and the presence of a dog elicited an increase in corticosterone and a decrease in GH levels in serum. While previous chronic stress induced a reduction of corticosterone response to the same stimuli, no reduction was observed in GH response. In addition, chronic exposure to noise-light stress induced modifications in corticosterone but not in GH response to dog presence. The results suggest that GH and corticoadrenal response mechanisms of adaptation to chronic stress are dissociated. This is further corroborated by the study of the correlation between both hormones.
Original languageEnglish
Pages (from-to)142-145
JournalHormone and Metabolic Research
Volume16
DOIs
Publication statusPublished - 1 Jan 1984

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