Dissociation between corticosterone and growth hormone adaptation to chronic stress in the rat

A. Armario, J. M. Castellanos

    Research output: Contribution to journalArticleResearchpeer-review

    21 Citations (Scopus)

    Abstract

    We have studied the effect of acute and chronic stress on corticosterone and growth hormone (GH) serum levels in male Wistar rats. Both acute noise-light stress and the presence of a dog elicited an increase in corticosterone and a decrease in GH levels in serum. While previous chronic stress induced a reduction of corticosterone response to the same stimuli, no reduction was observed in GH response. In addition, chronic exposure to noise-light stress induced modifications in corticosterone but not in GH response to dog presence. The results suggest that GH and corticoadrenal response mechanisms of adaptation to chronic stress are dissociated. This is further corroborated by the study of the correlation between both hormones.
    Original languageEnglish
    Pages (from-to)142-145
    JournalHormone and Metabolic Research
    Volume16
    DOIs
    Publication statusPublished - 1 Jan 1984

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