Disseminated Cryptococcus neoformans infection and Crohn's disease in an immunocompetent patient

Guido Sciaudone, Gianluca Pellino, Ilaria Guadagni, Anna Somma, Francesco P. D'Armiento, Francesco Selvaggi*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)


Cryptococcus neoformans is a human pathogen ubiquitously present in the environment. It primarily affects immunocompromised patients, but individuals with no underlying disease or immunodeficiency can also be affected.We herein describe the case of a patient found to have Crohn's disease and disseminated cryptococcosis simultaneously. She had no predisposing underlying cause for impaired immunity.Our patient showed signs that would have make it hard to discriminate between an inflammatory bowel disease and an infection if bowel only would have been involved. The patient underwent surgical intervention; medical therapy was effective against Cryptococcus. She is at now being followed-up for Crohn's disease.When dealing with patient affected with inflammatory bowel diseases, careful history taking, objective and instrumental examination are demandable in order not to overlook associated conditions or infectious diseases.Diagnosis and therapy of cryptococcosis infection in patient with Crohn's disease are herein discussed.

Original languageEnglish
Pages (from-to)60-63
Number of pages4
JournalJournal of Crohn's and Colitis
Issue number1
Publication statusPublished - Feb 2011


  • Crohn's disease
  • Cryptococcus neoformans
  • Disseminated cryptococcosis
  • Inflammatory bowel disease


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