Disseminated acute encephalomyelitis with fatal evolution: Clinicopathological study

A. Ortega-Aznar, F. J. Romero-Vidal, J. Salvadó

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4 Citations (Scopus)


Introduction. Disseminated acute encephalomyelitis is a monophasic demyelinating disease which progresses rapidly and is often fatal. It is an autoimmune condition, mediated by T lymphocytes, in which the immune response is directed against the myelin antigens. Clinical case. We describe the clinical, radiological and neuropathological findings in the case of a 31 year old woman who, ten days after complaining of a clinical condition of upper respiratory tract inflammation, presented with unilateral focal neurological signs, subsequent rapid deterioration of consciousness and death. On autopsy the neuropathological characteristics of disseminated acute encephalomyelitis were seen. Conclusions. The relative rarity of this condition at the present time makes clinical diagnosis difficult.The differential diagnosis with other conditions may be difficult also. Thus, this disease often leads to a neuropathological diagnosis. © 2000, Revista de Neurología.
Original languageEnglish
Pages (from-to)42-45
JournalRevista de Neurologia
Issue number1
Publication statusPublished - 1 Jul 2000


  • Autoimmune
  • Demyelinating diseases
  • Disseminated acute encephalomyelitis
  • Perivenous encephalomyelitis


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