Direct identification of Ruminococcus gnavus by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) on a positive anaerobic blood culture bottle

Dionisia Fontanals, Alex Larruzea, Isabel Sanfeliu

    Research output: Contribution to journalArticleResearch

    3 Citations (Scopus)

    Abstract

    © 2018 Elsevier Ltd We report a case of bloodstream infection with the anaerobic bacterium Ruminococcus gnavus (R. gnavus), associated with intestinal perforation in a patient undergoing chemotherapy for multiple myeloma and cancer of the sigmoid colon. Gram staining of positive anaerobic blood cultures revealed both diplococci and short chains of gram-positive cocci. MALDI-TOF MS done directly on the blood culture bottle identified the bacterium as R. gnavus, and 16S rRNA gene sequencing confirmed the identification.
    Original languageEnglish
    Pages (from-to)264-266
    JournalAnaerobe
    Volume54
    DOIs
    Publication statusPublished - 1 Dec 2018

    Keywords

    • Bloodstream infection
    • MALDI-TOF MS
    • Ruminococcus gnavus

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