Diffusion tensor imaging (DTI)

Silvia Lope-Piedrafita

doi:10.1007/978-1-4939-7531-0_7

Diffusion tensor imaging (DTI)

Silvia Lope-Piedrafita

Research output: Chapter in Book › Chapter › Research › peer-review

58 Citations (Scopus)

Abstract

© 2018, Springer Science+Business Media, LLC. Diffusion Tensor Imaging is an MRI technique that allows in vivo noninvasive measurement of the translational motion of water, providing information about its anisotropy (or lack of it) in different tissues. DTI has been commonly used to quantitatively measure the integrity of tissues which may be compromised by neurological disease, such as white matter tracks of the brain, which normally impart significant anisotropy to water motion in healthy brains. However, this anisotropic effect is diminished when axonal or neuronal damage is present. This chapter describes a standard protocol for DTI data acquisition in preclinical studies.

Original language	English
Title of host publication	Methods in Molecular Biology
Pages	103-116
Number of pages	13
Volume	1718
DOIs	https://doi.org/10.1007/978-1-4939-7531-0_7
Publication status	Published - 1 Jan 2018

Keywords

Apparent diffusion coefficient
Axial diffusivity
Diffusion tensor imaging
Fiber tracking
Fractional anisotropy
Radial diffusivity
White matter

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10.1007/978-1-4939-7531-0_7

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abstract = "{\textcopyright} 2018, Springer Science+Business Media, LLC. Diffusion Tensor Imaging is an MRI technique that allows in vivo noninvasive measurement of the translational motion of water, providing information about its anisotropy (or lack of it) in different tissues. DTI has been commonly used to quantitatively measure the integrity of tissues which may be compromised by neurological disease, such as white matter tracks of the brain, which normally impart significant anisotropy to water motion in healthy brains. However, this anisotropic effect is diminished when axonal or neuronal damage is present. This chapter describes a standard protocol for DTI data acquisition in preclinical studies.",

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KW - Apparent diffusion coefficient

KW - Axial diffusivity

KW - Diffusion tensor imaging

KW - Fiber tracking

KW - Fractional anisotropy

KW - Radial diffusivity

KW - White matter

U2 - 10.1007/978-1-4939-7531-0_7

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M3 - Chapter

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VL - 1718

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EP - 116

BT - Methods in Molecular Biology

ER -

Diffusion tensor imaging (DTI)

Abstract

Keywords

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