Differential reactivity of S-H bonds towards platinum(0). Direct synthesis of a low symmetry platinum(II) complex with hydrido, phosphine and N,S-cysteinato ethyl ester ligands

Julio Real; Alfonso Polo; Josep Duran

doi:10.1016/S1387-7003(98)00122-1

Differential reactivity of S-H bonds towards platinum(0). Direct synthesis of a low symmetry platinum(II) complex with hydrido, phosphine and N,S-cysteinato ethyl ester ligands

Julio Real, Alfonso Polo, Josep Duran

Department of Chemistry

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Abstract

The chelate assisted oxidative addition of the H-S bond of L-cysteine esters HSCH2C*H(COOR)NH2 (R = Me, Et), to Pt(PPh3)4 yields the low symmetry cysteine complexes [Pt(H) (SCH2C*H(COOR)NH2) (PPh3)] in one step, with displacement of three moles of triphenylphosphine, only when an excess of the cysteine ester is used. With HSCH2CH2NH2 the excess is not necessary: the 1:1 reaction yields [Pt(H) (SCH2CH2NH2) (PPh3)]. Bulkier HSCH2CH2NMe2 and HSCMe2CH(COOMe)NH2 (penicillamine methyl ester) do not react, even when an excess of ligand is used. 2-Aminothiophenol gives trans-[Pt(H) (SC6H4-2-NH2) (PPh3)2] and does not form a chelate complex. © 1998 Elsevier Science S.A. All rights reserved.

Original language	English
Pages (from-to)	457-459
Journal	Inorganic Chemistry Communications
Volume	1
Issue number	12
DOIs	https://doi.org/10.1016/S1387-7003(98)00122-1
Publication status	Published - 1 Jan 1998

Keywords

Cysteine complexes
Hydrido complexes
Platinum complexes

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10.1016/S1387-7003(98)00122-1

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title = "Differential reactivity of S-H bonds towards platinum(0). Direct synthesis of a low symmetry platinum(II) complex with hydrido, phosphine and N,S-cysteinato ethyl ester ligands",

abstract = "The chelate assisted oxidative addition of the H-S bond of L-cysteine esters HSCH2C*H(COOR)NH2 (R = Me, Et), to Pt(PPh3)4 yields the low symmetry cysteine complexes [Pt(H) (SCH2C*H(COOR)NH2) (PPh3)] in one step, with displacement of three moles of triphenylphosphine, only when an excess of the cysteine ester is used. With HSCH2CH2NH2 the excess is not necessary: the 1:1 reaction yields [Pt(H) (SCH2CH2NH2) (PPh3)]. Bulkier HSCH2CH2NMe2 and HSCMe2CH(COOMe)NH2 (penicillamine methyl ester) do not react, even when an excess of ligand is used. 2-Aminothiophenol gives trans-[Pt(H) (SC6H4-2-NH2) (PPh3)2] and does not form a chelate complex. {\textcopyright} 1998 Elsevier Science S.A. All rights reserved.",

keywords = "Cysteine complexes, Hydrido complexes, Platinum complexes",

author = "Julio Real and Alfonso Polo and Josep Duran",

year = "1998",

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doi = "10.1016/S1387-7003(98)00122-1",

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Differential reactivity of S-H bonds towards platinum(0). Direct synthesis of a low symmetry platinum(II) complex with hydrido, phosphine and N,S-cysteinato ethyl ester ligands. / Real, Julio; Polo, Alfonso; Duran, Josep.

In: Inorganic Chemistry Communications, Vol. 1, No. 12, 01.01.1998, p. 457-459.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Differential reactivity of S-H bonds towards platinum(0). Direct synthesis of a low symmetry platinum(II) complex with hydrido, phosphine and N,S-cysteinato ethyl ester ligands

AU - Real, Julio

AU - Polo, Alfonso

AU - Duran, Josep

PY - 1998/1/1

Y1 - 1998/1/1

N2 - The chelate assisted oxidative addition of the H-S bond of L-cysteine esters HSCH2C*H(COOR)NH2 (R = Me, Et), to Pt(PPh3)4 yields the low symmetry cysteine complexes [Pt(H) (SCH2C*H(COOR)NH2) (PPh3)] in one step, with displacement of three moles of triphenylphosphine, only when an excess of the cysteine ester is used. With HSCH2CH2NH2 the excess is not necessary: the 1:1 reaction yields [Pt(H) (SCH2CH2NH2) (PPh3)]. Bulkier HSCH2CH2NMe2 and HSCMe2CH(COOMe)NH2 (penicillamine methyl ester) do not react, even when an excess of ligand is used. 2-Aminothiophenol gives trans-[Pt(H) (SC6H4-2-NH2) (PPh3)2] and does not form a chelate complex. © 1998 Elsevier Science S.A. All rights reserved.

AB - The chelate assisted oxidative addition of the H-S bond of L-cysteine esters HSCH2C*H(COOR)NH2 (R = Me, Et), to Pt(PPh3)4 yields the low symmetry cysteine complexes [Pt(H) (SCH2C*H(COOR)NH2) (PPh3)] in one step, with displacement of three moles of triphenylphosphine, only when an excess of the cysteine ester is used. With HSCH2CH2NH2 the excess is not necessary: the 1:1 reaction yields [Pt(H) (SCH2CH2NH2) (PPh3)]. Bulkier HSCH2CH2NMe2 and HSCMe2CH(COOMe)NH2 (penicillamine methyl ester) do not react, even when an excess of ligand is used. 2-Aminothiophenol gives trans-[Pt(H) (SC6H4-2-NH2) (PPh3)2] and does not form a chelate complex. © 1998 Elsevier Science S.A. All rights reserved.

KW - Cysteine complexes

KW - Hydrido complexes

KW - Platinum complexes

U2 - 10.1016/S1387-7003(98)00122-1

DO - 10.1016/S1387-7003(98)00122-1

M3 - Article

VL - 1

SP - 457

EP - 459

IS - 12

ER -

Differential reactivity of S-H bonds towards platinum(0). Direct synthesis of a low symmetry platinum(II) complex with hydrido, phosphine and N,S-cysteinato ethyl ester ligands

Abstract

Keywords

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