The chelate assisted oxidative addition of the H-S bond of L-cysteine esters HSCH2C*H(COOR)NH2 (R = Me, Et), to Pt(PPh3)4 yields the low symmetry cysteine complexes [Pt(H) (SCH2C*H(COOR)NH2) (PPh3)] in one step, with displacement of three moles of triphenylphosphine, only when an excess of the cysteine ester is used. With HSCH2CH2NH2 the excess is not necessary: the 1:1 reaction yields [Pt(H) (SCH2CH2NH2) (PPh3)]. Bulkier HSCH2CH2NMe2 and HSCMe2CH(COOMe)NH2 (penicillamine methyl ester) do not react, even when an excess of ligand is used. 2-Aminothiophenol gives trans-[Pt(H) (SC6H4-2-NH2) (PPh3)2] and does not form a chelate complex. © 1998 Elsevier Science S.A. All rights reserved.
|Journal||Inorganic Chemistry Communications|
|Publication status||Published - 1 Jan 1998|
- Cysteine complexes
- Hydrido complexes
- Platinum complexes