Objective: To analyze the agreement in glomerular filtration rate (GFR) estimated with CKD-EPI and MDRD-IDMS equations in a cohort of hypertensive patients. Methods: We included consecutively 478 hypertensive patients, 57.58 (SD: 12.34) aged, 68.3% males. The estimation of GFR was performed with MDRD-IDMS and CKD-EPI equations and we analyzed the agreement between them. Results: The estimation of GFR with CKD-EPI was 4.37 (95%:3,73-4,19) mL/min/1,73 m2higher than MDRD-IDMS, overall and by gender (males 3.99; females 5.04). In patients under 65 years the difference was greater, 6.55 (95%: 5,95-7,15) ml/min/1,73 m2in both men 6.07 and women 6.48. However, in over 65 years we found no significant difference. Intraclass correlation coefficient was 0.904 (95%CI: 0,886-0,919), 0.897 men and 0.917 women and Kappa index 0.848 (95% CI: 0.795-0.889), 0.845 men and 0.852 women. Conclusion: CKD-EPI equation estimated a higher FG in hypertensive patients under 65 years and reclassified in stage 1 patients classified in stage 2 by MDRD-IDMS. © 2010 Revista Nefrología.
|Publication status||Published - 31 Aug 2010|
- Blood pressure
- Glomerular filtration rate
- Kidney diseases