TY - JOUR
T1 - Differences in the CKD-EPI equation with MDRD for the estimation of glomerular filtration in hypertensive patients
AU - Gómez Marcos, M. A.
AU - Rodríguez Sánchez, E.
AU - Recio Rodríguez, J. I.
AU - Martín Cantera, C.
AU - Ramos Blanes, R.
AU - García Ortiz, L.
PY - 2010/8/31
Y1 - 2010/8/31
N2 - Objective: To analyze the agreement in glomerular filtration rate (GFR) estimated with CKD-EPI and MDRD-IDMS equations in a cohort of hypertensive patients. Methods: We included consecutively 478 hypertensive patients, 57.58 (SD: 12.34) aged, 68.3% males. The estimation of GFR was performed with MDRD-IDMS and CKD-EPI equations and we analyzed the agreement between them. Results: The estimation of GFR with CKD-EPI was 4.37 (95%:3,73-4,19) mL/min/1,73 m2higher than MDRD-IDMS, overall and by gender (males 3.99; females 5.04). In patients under 65 years the difference was greater, 6.55 (95%: 5,95-7,15) ml/min/1,73 m2in both men 6.07 and women 6.48. However, in over 65 years we found no significant difference. Intraclass correlation coefficient was 0.904 (95%CI: 0,886-0,919), 0.897 men and 0.917 women and Kappa index 0.848 (95% CI: 0.795-0.889), 0.845 men and 0.852 women. Conclusion: CKD-EPI equation estimated a higher FG in hypertensive patients under 65 years and reclassified in stage 1 patients classified in stage 2 by MDRD-IDMS. © 2010 Revista Nefrología.
AB - Objective: To analyze the agreement in glomerular filtration rate (GFR) estimated with CKD-EPI and MDRD-IDMS equations in a cohort of hypertensive patients. Methods: We included consecutively 478 hypertensive patients, 57.58 (SD: 12.34) aged, 68.3% males. The estimation of GFR was performed with MDRD-IDMS and CKD-EPI equations and we analyzed the agreement between them. Results: The estimation of GFR with CKD-EPI was 4.37 (95%:3,73-4,19) mL/min/1,73 m2higher than MDRD-IDMS, overall and by gender (males 3.99; females 5.04). In patients under 65 years the difference was greater, 6.55 (95%: 5,95-7,15) ml/min/1,73 m2in both men 6.07 and women 6.48. However, in over 65 years we found no significant difference. Intraclass correlation coefficient was 0.904 (95%CI: 0,886-0,919), 0.897 men and 0.917 women and Kappa index 0.848 (95% CI: 0.795-0.889), 0.845 men and 0.852 women. Conclusion: CKD-EPI equation estimated a higher FG in hypertensive patients under 65 years and reclassified in stage 1 patients classified in stage 2 by MDRD-IDMS. © 2010 Revista Nefrología.
KW - Blood pressure
KW - Calibration
KW - Creatinine
KW - Diagnosis
KW - Epidemiology
KW - Glomerular filtration rate
KW - Kidney diseases
U2 - https://doi.org/10.3265/Nefrologia.pre2010.Mar.10321
DO - https://doi.org/10.3265/Nefrologia.pre2010.Mar.10321
M3 - Article
SN - 0211-6995
VL - 30
SP - 458
EP - 462
JO - Nefrologia
JF - Nefrologia
ER -