Diastereoselective synthesis of allosecurinine and viroallosecurinine from menisdaurilide

Gisela G. Bardají, Mariona Cantó, Ramón Alibés, Pau Bayón, Félix Busqué, Pedro De March, Marta Figueredo, Josep Font

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Abstract

(Chemical Equation Presented) A new and versatile synthetic route to Securinega alkaloids is reported. The first synthesis of allosecurinine has been accomplished in seven steps and 40% yield, starting from (+)-menisdaurilide, using a vinylogous Mannich reaction as the key transformation. Similarly, viroallosecurinine has been synthesized from (-)-menisdaurilide. © 2008 American Chemical Society.
Original languageEnglish
Pages (from-to)7657-7662
JournalJournal of Organic Chemistry
Volume73
Issue number19
DOIs
Publication statusPublished - 3 Oct 2008

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