Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines

Irene Litvan, Jennifer G. Goldman, Alexander I. Tröster, Ben A. Schmand, Daniel Weintraub, Ronald C. Petersen, Brit Mollenhauer, Charles H. Adler, Karen Marder, Caroline H. Williams-Gray, Dag Aarsland, Jaime Kulisevsky, Maria C. Rodriguez-Oroz, David J. Burn, Roger A. Barker, Murat Emre

Research output: Contribution to journalArticleResearchpeer-review

1091 Citations (Scopus)

Abstract

Mild cognitive impairment is common in nondemented Parkinson's disease (PD) patients and may be a harbinger of dementia. In view of its importance, the Movement Disorder Society commissioned a task force to delineate diagnostic criteria for mild cognitive impairment in PD. The proposed diagnostic criteria are based on a literature review and expert consensus. This article provides guidelines to characterize the clinical syndrome and methods for its diagnosis. The criteria will require validation, and possibly refinement, as additional research improves our understanding of the epidemiology, presentation, neurobiology, assessment, and long-term course of this clinical syndrome. These diagnostic criteria will support future research efforts to identify at the earliest stage those PD patients at increased risk of progressive cognitive decline and dementia who may benefit from clinical interventions at a predementia stage. © 2012 Movement Disorder Society.
Original languageEnglish
Pages (from-to)349-356
JournalMovement Disorders
Volume27
Issue number3
DOIs
Publication statusPublished - 1 Mar 2012

Keywords

  • Cognition
  • Dementia
  • Diagnostic criteria
  • Mild cognitive impairment
  • Parkinson's disease

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