Diagnosis of Helicobacter pylori Infection

Xavier Calvet, Philippe Lehours, Sergio Lario, Francis Mégraud

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Abstract

If we had to give a general view of the articles published in the year 2010, we should conclude that the evidence in the year 2010 suggests that, also in Helicobacter pylori diagnosis, "the devil is in the details". In this sense, different studies suggested that skipping citric acid pretreatment or local validation or reducing the 13C-urea dose markedly decreases the accuracy of the urea breath test. The studies also implied that, even between monoclonal stool tests, there are large differences between the marketed tests. Finally, even histology does not work adequately in patients with gastric cancer or extensive areas of intestinal metaplasia. In these cases, specific gastric sites should be biopsied to improve the reliability of histology. © 2010 Blackwell Publishing Ltd.
Original languageEnglish
Pages (from-to)7-13
JournalHelicobacter
Volume15
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 1 Jan 2010

Keywords

  • Endoscopy
  • Histology
  • Molecular tests
  • Serology
  • Stool test
  • Urea breath test

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