Detection and characterization of emerging psychoactive substances by ion mobility spectrometry

Sergio Armenta; Salvador Garrigues; Miguel de la Guardia; Judit Brassier; Manel Alcalà; Marcelo Blanco; Clara Perez-Alfonso; Nieves Galipienso

doi:10.1002/dta.1678

Detection and characterization of emerging psychoactive substances by ion mobility spectrometry

Sergio Armenta, Salvador Garrigues, Miguel de la Guardia, Judit Brassier, Manel Alcalà, Marcelo Blanco, Clara Perez-Alfonso, Nieves Galipienso

Research output: Contribution to journal › Article › Research › peer-review

32 Citations (Scopus)

Abstract

© 2014 John Wiley & Sons, Ltd. Rapid detection and identification of novel psychoactive substances (NPS) continues to present significant analytical challenges to forensic and analytical chemists. Ion mobility spectrometry (IMS) has been traditionally considered as the analytical technique of choice to detect illicit drugs in security points in airports, borderlines and customs. Databases of the reduced mobility (K0) values of illicit drugs are available in the scientific literature and they should be completed with data of emerging designer drugs. In this paper, we have evaluated the effect of different measurement conditions and determined the K0 values of an important number of NPS including different families; such as phenethylamines, cathinones, synthetic cannabinoids and tryptamines among others to be incorporated to the existing data to provide a rapid detection and identification of this emerging threat.

Original language	English
Pages (from-to)	280-289
Journal	Drug Testing and Analysis
Volume	7
Issue number	4
DOIs	https://doi.org/10.1002/dta.1678
Publication status	Published - 1 Apr 2015

Keywords

Amphetamine derivatives
Cathinones
Designer drugs
Ion mobility spectrometry
Synthetic cannabinoids
Tryptamines

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10.1002/dta.1678

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abstract = "{\textcopyright} 2014 John Wiley & Sons, Ltd. Rapid detection and identification of novel psychoactive substances (NPS) continues to present significant analytical challenges to forensic and analytical chemists. Ion mobility spectrometry (IMS) has been traditionally considered as the analytical technique of choice to detect illicit drugs in security points in airports, borderlines and customs. Databases of the reduced mobility (K0) values of illicit drugs are available in the scientific literature and they should be completed with data of emerging designer drugs. In this paper, we have evaluated the effect of different measurement conditions and determined the K0 values of an important number of NPS including different families; such as phenethylamines, cathinones, synthetic cannabinoids and tryptamines among others to be incorporated to the existing data to provide a rapid detection and identification of this emerging threat.",

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AU - Armenta, Sergio

AU - Garrigues, Salvador

AU - de la Guardia, Miguel

AU - Brassier, Judit

AU - Alcalà, Manel

AU - Blanco, Marcelo

AU - Perez-Alfonso, Clara

AU - Galipienso, Nieves

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N2 - © 2014 John Wiley & Sons, Ltd. Rapid detection and identification of novel psychoactive substances (NPS) continues to present significant analytical challenges to forensic and analytical chemists. Ion mobility spectrometry (IMS) has been traditionally considered as the analytical technique of choice to detect illicit drugs in security points in airports, borderlines and customs. Databases of the reduced mobility (K0) values of illicit drugs are available in the scientific literature and they should be completed with data of emerging designer drugs. In this paper, we have evaluated the effect of different measurement conditions and determined the K0 values of an important number of NPS including different families; such as phenethylamines, cathinones, synthetic cannabinoids and tryptamines among others to be incorporated to the existing data to provide a rapid detection and identification of this emerging threat.

AB - © 2014 John Wiley & Sons, Ltd. Rapid detection and identification of novel psychoactive substances (NPS) continues to present significant analytical challenges to forensic and analytical chemists. Ion mobility spectrometry (IMS) has been traditionally considered as the analytical technique of choice to detect illicit drugs in security points in airports, borderlines and customs. Databases of the reduced mobility (K0) values of illicit drugs are available in the scientific literature and they should be completed with data of emerging designer drugs. In this paper, we have evaluated the effect of different measurement conditions and determined the K0 values of an important number of NPS including different families; such as phenethylamines, cathinones, synthetic cannabinoids and tryptamines among others to be incorporated to the existing data to provide a rapid detection and identification of this emerging threat.

KW - Amphetamine derivatives

KW - Cathinones

KW - Designer drugs

KW - Ion mobility spectrometry

KW - Synthetic cannabinoids

KW - Tryptamines

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DO - 10.1002/dta.1678

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JO - Drug Testing and Analysis

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Detection and characterization of emerging psychoactive substances by ion mobility spectrometry

Abstract

Keywords

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