Delphi consensus on management of dyslipidaemia in patients with impaired glucose metabolism: Diana study

Juan Pedro-Botet, Vivencio Barrios, Vicente Pascual, Juan F. Ascaso, Aleix Cases, Jesús Millán, Adalberto Serrano, Xavier Pintó

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3 Citations (Scopus)

Abstract

© 2016 Sociedad Española de Arteriosclerosis. Objectives: The aim of the present study was to develop a multidisciplinary consensus based on the Delphi system to establish clinical recommendations for the management of dyslipidaemia when hyperglycaemia is present, and the relevant factors that should be taken into consideration when prescribing and monitoring treatment with statins. Methods: The questionnaire developed by the scientific committee included four blocks of questions about dyslipidaemia in patients with impaired glucose metabolism. The results of the first two blocks are presented here: a) management of dyslipidaemia; b) relevant factors that should be taken into consideration when prescribing and monitoring treatment with statins. Results: Among the 497 experts who participated in the study, an agreement of over 90% was attained for recommending screening for dyslipidaemia in patients with diabetes or pre-diabetes and/or cardiovascular disease or a family history and/or abdominal obesity and/or hypertension. There was a high degree of agreement that a statin is the lipid-lowering treatment of choice, and that it should be switched when side effects develop. Also, the choice of statin and dose should be made according to baseline LDL cholesterol levels, the target to achieve, and the possible drug-drug interactions. Conclusions: The screening of dyslipidaemia is primarily conducted in patients with cardiovascular disease, or any major cardiovascular risk factor. When prescribing a statin, physicians mainly focus on the ability to reduce LDL cholesterol and the risk of drug interactions.
Original languageEnglish
Pages (from-to)132-140
JournalClinica e Investigacion en Arteriosclerosis
Volume28
Issue number3
DOIs
Publication statusPublished - 1 May 2016

Keywords

  • Cardiovascular disease
  • Glucose metabolism disorders
  • Glycosilated heamoglobin
  • Prevention
  • Statins
  • Type 2 diabetes mellitus

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