Cytogenetic studies in motile sperm from normal men

J. Benet; A. Genescà; J. Navarro; J. Egozcue; C. Templado

doi:10.1007/BF00217119

Cytogenetic studies in motile sperm from normal men

J. Benet, A. Genescà, J. Navarro, J. Egozcue, C. Templado

Institute of Biotechnology and Biomedicine "Vicent Villar Palasi" (IBB)

Research output: Contribution to journal › Article › Research › peer-review

37 Citations (Scopus)

Abstract

Most studies on human sperm chromosomes from normal men involve the heterologous fertilization of zona free hamster eggs by unselected human sperm. In this work, we have performed cytogenetic studies of highly motile sperm, selected by a swim-up method. A total of 505 motile human sperm complements from three normal donors was analysed. The total frequency of sperm with chromosomal abnormalities (10.9%; 6.9% structural aberrations and 4.0% aneuploidy) and the sex ratio (50.4% X:49.6% Y) were similar to those obtained from whole semen samples. Our results indicate that the selection of motile sperm does not imply chromosomal selection. © 1992 Springer-Verlag.

Original language	English
Pages (from-to)	176-180
Journal	Human Genetics
Volume	89
Issue number	2
DOIs	https://doi.org/10.1007/BF00217119
Publication status	Published - 1 May 1992

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title = "Cytogenetic studies in motile sperm from normal men",

abstract = "Most studies on human sperm chromosomes from normal men involve the heterologous fertilization of zona free hamster eggs by unselected human sperm. In this work, we have performed cytogenetic studies of highly motile sperm, selected by a swim-up method. A total of 505 motile human sperm complements from three normal donors was analysed. The total frequency of sperm with chromosomal abnormalities (10.9%; 6.9% structural aberrations and 4.0% aneuploidy) and the sex ratio (50.4% X:49.6% Y) were similar to those obtained from whole semen samples. Our results indicate that the selection of motile sperm does not imply chromosomal selection. {\textcopyright} 1992 Springer-Verlag.",

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AU - Benet, J.

AU - Genescà, A.

AU - Navarro, J.

AU - Egozcue, J.

AU - Templado, C.

PY - 1992/5/1

Y1 - 1992/5/1

N2 - Most studies on human sperm chromosomes from normal men involve the heterologous fertilization of zona free hamster eggs by unselected human sperm. In this work, we have performed cytogenetic studies of highly motile sperm, selected by a swim-up method. A total of 505 motile human sperm complements from three normal donors was analysed. The total frequency of sperm with chromosomal abnormalities (10.9%; 6.9% structural aberrations and 4.0% aneuploidy) and the sex ratio (50.4% X:49.6% Y) were similar to those obtained from whole semen samples. Our results indicate that the selection of motile sperm does not imply chromosomal selection. © 1992 Springer-Verlag.

AB - Most studies on human sperm chromosomes from normal men involve the heterologous fertilization of zona free hamster eggs by unselected human sperm. In this work, we have performed cytogenetic studies of highly motile sperm, selected by a swim-up method. A total of 505 motile human sperm complements from three normal donors was analysed. The total frequency of sperm with chromosomal abnormalities (10.9%; 6.9% structural aberrations and 4.0% aneuploidy) and the sex ratio (50.4% X:49.6% Y) were similar to those obtained from whole semen samples. Our results indicate that the selection of motile sperm does not imply chromosomal selection. © 1992 Springer-Verlag.

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