Cytogenetic analysis of lymphocytes from hospital workers occupationally exposed to low levels of ionizing radiation

J. F. Barquinero; L. Barrios; M. R. Caballín; R. Miró; M. Ribas; A. Subias; J. Egozcue

doi:10.1016/0027-5107(93)90192-I

Cytogenetic analysis of lymphocytes from hospital workers occupationally exposed to low levels of ionizing radiation

J. F. Barquinero, L. Barrios, M. R. Caballín, R. Miró, M. Ribas, A. Subias, J. Egozcue

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Abstract

Cytogenetic studies were performed in lymphocytes from hospital workers exposed to low doses of radiation (1.6-42.71 mSv). When compared with controls, exposed workers showed a significant increase in structural chromosome-type aberrations, acentric fragments being the most frequent alteration. Our results suggest that acentric fragments are good indicators of exposure to very low doses of radiation, although no dose-effect correlation was observed. The incidence of numerical abnormalities (hyperdiploidy) was significantly increased. © 1993.

Original language	English
Pages (from-to)	275-279
Journal	Mutation Research
Volume	286
DOIs	https://doi.org/10.1016/0027-5107(93)90192-I
Publication status	Published - 1 Jan 1993

Keywords

Chromosome aberrations
Occupational exposure
Peripheral blood lymphocytes

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10.1016/0027-5107(93)90192-I

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title = "Cytogenetic analysis of lymphocytes from hospital workers occupationally exposed to low levels of ionizing radiation",

abstract = "Cytogenetic studies were performed in lymphocytes from hospital workers exposed to low doses of radiation (1.6-42.71 mSv). When compared with controls, exposed workers showed a significant increase in structural chromosome-type aberrations, acentric fragments being the most frequent alteration. Our results suggest that acentric fragments are good indicators of exposure to very low doses of radiation, although no dose-effect correlation was observed. The incidence of numerical abnormalities (hyperdiploidy) was significantly increased. {\textcopyright} 1993.",

keywords = "Chromosome aberrations, Occupational exposure, Peripheral blood lymphocytes",

author = "Barquinero, {J. F.} and L. Barrios and Caball{\'i}n, {M. R.} and R. Mir{\'o} and M. Ribas and A. Subias and J. Egozcue",

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AU - Barquinero, J. F.

AU - Barrios, L.

AU - Caballín, M. R.

AU - Miró, R.

AU - Ribas, M.

AU - Subias, A.

AU - Egozcue, J.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - Cytogenetic studies were performed in lymphocytes from hospital workers exposed to low doses of radiation (1.6-42.71 mSv). When compared with controls, exposed workers showed a significant increase in structural chromosome-type aberrations, acentric fragments being the most frequent alteration. Our results suggest that acentric fragments are good indicators of exposure to very low doses of radiation, although no dose-effect correlation was observed. The incidence of numerical abnormalities (hyperdiploidy) was significantly increased. © 1993.

AB - Cytogenetic studies were performed in lymphocytes from hospital workers exposed to low doses of radiation (1.6-42.71 mSv). When compared with controls, exposed workers showed a significant increase in structural chromosome-type aberrations, acentric fragments being the most frequent alteration. Our results suggest that acentric fragments are good indicators of exposure to very low doses of radiation, although no dose-effect correlation was observed. The incidence of numerical abnormalities (hyperdiploidy) was significantly increased. © 1993.

KW - Chromosome aberrations

KW - Occupational exposure

KW - Peripheral blood lymphocytes

U2 - 10.1016/0027-5107(93)90192-I

DO - 10.1016/0027-5107(93)90192-I

M3 - Article

SN - 0027-5107

VL - 286

SP - 275

EP - 279

JO - Mutation Research

JF - Mutation Research

ER -

Cytogenetic analysis of lymphocytes from hospital workers occupationally exposed to low levels of ionizing radiation

Abstract

Keywords

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