Cytogenetic analysis of lymphocytes from hospital workers occupationally exposed to low levels of ionizing radiation

J. F. Barquinero, L. Barrios, M. R. Caballín, R. Miró, M. Ribas, A. Subias, J. Egozcue

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94 Citations (Scopus)

Abstract

Cytogenetic studies were performed in lymphocytes from hospital workers exposed to low doses of radiation (1.6-42.71 mSv). When compared with controls, exposed workers showed a significant increase in structural chromosome-type aberrations, acentric fragments being the most frequent alteration. Our results suggest that acentric fragments are good indicators of exposure to very low doses of radiation, although no dose-effect correlation was observed. The incidence of numerical abnormalities (hyperdiploidy) was significantly increased. © 1993.
Original languageEnglish
Pages (from-to)275-279
JournalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume286
DOIs
Publication statusPublished - 1 Jan 1993

Keywords

  • Chromosome aberrations
  • Occupational exposure
  • Peripheral blood lymphocytes

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