Cutaneous Light Chain Deposition Disease: A Report of 2 Cases and Review of the Literature

Carlo Hendricks, Maite T. Fernández Figueras, Julia Liersch, Maria Teresa Martin-Urdà, Dolores López, Christoph Brochhausen, Christoph Röcken, Jörg Schaller

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved. Light chain deposition disease (LCDD) is a rare systemic disorder with deposition of mostly monoclonal amorphous nonamyloid light chains in multiple organs. Renal involvement with rapidly progressing renal failure presents the dominant manifestation of LCDD. Approximately 20%-30% of patients show symptomatic cardiac or liver involvement. Cutaneous manifestations are extremely rare with only a few published cases. We report 2 additional cases of cutaneous LCDD without detectable systemic disease.
    Original languageEnglish
    Pages (from-to)337-341
    JournalAmerican Journal of Dermatopathology
    Volume40
    Issue number5
    DOIs
    Publication statusPublished - 1 May 2018

    Keywords

    • cutaneous deposition diseases
    • light chain deposition disease
    • nonamyloid eosinophilic amorphous cutaneous deposition

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