Crowding-induced changes in basal and stress levels of thyrotropin and somatotropin in male rats

A. Armario; C. Garcia-Marquez; T. Jolin

doi:https://doi.org/10.1016/S0163-1047(87)90892-2

Crowding-induced changes in basal and stress levels of thyrotropin and somatotropin in male rats

A. Armario, C. Garcia-Marquez, T. Jolin

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Abstract

The effects of crowding on thyrotropin (TSH) and somatotropin (GH) secretion were studied in two-month-old male rats. Crowded rats (9-10 per cage) showed lower serum GH levels than controls (3 per cage). Likewise, serum GH was lower in crowded rats after acute exposure to stress. However, percentage inhibition of GH secretion induced by acute stress was similar in crowded and control rats. Crowding reduced the TSH response to acute stress. The results found with the administration of hypothalamic regulatory factors suggest that the impaired GH and TSH secretion observed in crowded rats was not likely to be at the pituitary level. Therefore, altered neuroendocrine control of GH and TSH secretion appears to exist in crowded rats. Preliminary results obtained in rats crowded from weaning to adulthood suggest that food restriction only partially accounts for the changes observed in crowded rats. © 1987 Academic Press, Inc.

Original language	English
Pages (from-to)	334-343
Journal	Behavioral and Neural Biology
Volume	48
DOIs	https://doi.org/10.1016/S0163-1047(87)90892-2
Publication status	Published - 1 Jan 1987

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title = "Crowding-induced changes in basal and stress levels of thyrotropin and somatotropin in male rats",

abstract = "The effects of crowding on thyrotropin (TSH) and somatotropin (GH) secretion were studied in two-month-old male rats. Crowded rats (9-10 per cage) showed lower serum GH levels than controls (3 per cage). Likewise, serum GH was lower in crowded rats after acute exposure to stress. However, percentage inhibition of GH secretion induced by acute stress was similar in crowded and control rats. Crowding reduced the TSH response to acute stress. The results found with the administration of hypothalamic regulatory factors suggest that the impaired GH and TSH secretion observed in crowded rats was not likely to be at the pituitary level. Therefore, altered neuroendocrine control of GH and TSH secretion appears to exist in crowded rats. Preliminary results obtained in rats crowded from weaning to adulthood suggest that food restriction only partially accounts for the changes observed in crowded rats. {\textcopyright} 1987 Academic Press, Inc.",

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T1 - Crowding-induced changes in basal and stress levels of thyrotropin and somatotropin in male rats

AU - Armario, A.

AU - Garcia-Marquez, C.

AU - Jolin, T.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - The effects of crowding on thyrotropin (TSH) and somatotropin (GH) secretion were studied in two-month-old male rats. Crowded rats (9-10 per cage) showed lower serum GH levels than controls (3 per cage). Likewise, serum GH was lower in crowded rats after acute exposure to stress. However, percentage inhibition of GH secretion induced by acute stress was similar in crowded and control rats. Crowding reduced the TSH response to acute stress. The results found with the administration of hypothalamic regulatory factors suggest that the impaired GH and TSH secretion observed in crowded rats was not likely to be at the pituitary level. Therefore, altered neuroendocrine control of GH and TSH secretion appears to exist in crowded rats. Preliminary results obtained in rats crowded from weaning to adulthood suggest that food restriction only partially accounts for the changes observed in crowded rats. © 1987 Academic Press, Inc.

AB - The effects of crowding on thyrotropin (TSH) and somatotropin (GH) secretion were studied in two-month-old male rats. Crowded rats (9-10 per cage) showed lower serum GH levels than controls (3 per cage). Likewise, serum GH was lower in crowded rats after acute exposure to stress. However, percentage inhibition of GH secretion induced by acute stress was similar in crowded and control rats. Crowding reduced the TSH response to acute stress. The results found with the administration of hypothalamic regulatory factors suggest that the impaired GH and TSH secretion observed in crowded rats was not likely to be at the pituitary level. Therefore, altered neuroendocrine control of GH and TSH secretion appears to exist in crowded rats. Preliminary results obtained in rats crowded from weaning to adulthood suggest that food restriction only partially accounts for the changes observed in crowded rats. © 1987 Academic Press, Inc.

U2 - https://doi.org/10.1016/S0163-1047(87)90892-2

DO - https://doi.org/10.1016/S0163-1047(87)90892-2

M3 - Article

VL - 48

SP - 334

EP - 343

ER -

Crowding-induced changes in basal and stress levels of thyrotropin and somatotropin in male rats

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