Critical role of substrate conformational change in the proton transfer process catalyzed by 4-oxalocrotonate tautomerase

Engineering & Materials Science

• Proton transfer 84%
• Substrates 32%
• Isomerization 26%
• Atoms 19%
• Nitrogen 17%
• Potential energy surfaces 15%
• Energy barriers 14%
• Carbon 13%
• Rate constants 11%
• Free energy 11%
• Enzymes 10%
• Electrons 9%
• Trajectories 6%

Medicine & Life Sciences

• 4-oxalocrotonate tautomerase 100%
• Protons 47%
• Carbon 22%
• Nitrogen 22%
• Chemical Phenomena 16%
• Proline 12%
• Catalytic Domain 10%
• Electrons 9%
• Enzymes 6%

Chemistry

• Proton Transfer 41%
• Isomerization 18%
• Corresponding State 16%
• Electron Configuration 14%
• Transition State Theory 13%
• Proline 11%
• Tunneling 11%
• Statistical Ensemble 11%
• Energy Barrier 11%
• Potential Energy Surface 11%
• Carbon Atom 10%
• Nitrogen Atom 9%
• Transition State 9%
• Flexibility 9%
• Gibbs Free Energy 8%
• Rate Constant 7%
• Simulation 7%
• Nitrogen 6%
• Energy 5%