TY - JOUR
T1 - CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii
AU - Roca, I.
AU - Marti, S.
AU - Espinal, P.
AU - Martínez, P.
AU - Gibert, I.
AU - Vila, J.
PY - 2009/9/21
Y1 - 2009/9/21
N2 - Acinetobacter baumannii has been increasingly associated with hospital-acquired infections, and the presence of multidrug resistance strains is of great concern to clinicians. A. baumannii is thought to possess a great deal of intrinsic resistance to several antimicrobial agents, including chloramphenicol, although the mechanisms involved in such resistance are not well understood. In this work, we have identified a major facilitator superfamily efflux pump present in most A. baumannii strains, displaying strong substrate specificity toward chloramphenicol. Copyright © 2009, American Society for Microbiology. All Rights Reserved.
AB - Acinetobacter baumannii has been increasingly associated with hospital-acquired infections, and the presence of multidrug resistance strains is of great concern to clinicians. A. baumannii is thought to possess a great deal of intrinsic resistance to several antimicrobial agents, including chloramphenicol, although the mechanisms involved in such resistance are not well understood. In this work, we have identified a major facilitator superfamily efflux pump present in most A. baumannii strains, displaying strong substrate specificity toward chloramphenicol. Copyright © 2009, American Society for Microbiology. All Rights Reserved.
U2 - https://doi.org/10.1128/AAC.00584-09
DO - https://doi.org/10.1128/AAC.00584-09
M3 - Article
VL - 53
SP - 4013
EP - 4014
ER -