The literature concerning the action of corticosteroids in the treatment of shock is reviewed. Although it appears evident that there is no adrenal failure in shock, all the authors agree upon high dose therapy. The mode of action is not understood but nevertheless there is constant evidence that the survival rate is increased. The review concludes with an account of the actions of the corticosteroids on blood vessels, cells, heart, kidney and liver and their protective action against the effects of endotoxin on the body. Forty three references are cited.
|Publication status||Published - 1 Jan 1974|